Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies

PurposeTo compare the 3D-printed oral stents (3D-OS) and personalised hand-made stents in dentistry (DentStent) for head and neck malignancies.MethodsTwelve patients with head and neck malignant tumours in the Cancer Centre of Shanxi Bethune Hospital from 1 August 2023 to 31 September 2024 were admi...

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Main Authors: Shihang Li, Guobao Pang, Rong Li, Qinying Shi, Yannan Xu, Ying Lu, Jianbo Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1544105/full
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author Shihang Li
Guobao Pang
Rong Li
Rong Li
Qinying Shi
Yannan Xu
Yannan Xu
Ying Lu
Ying Lu
Jianbo Song
author_facet Shihang Li
Guobao Pang
Rong Li
Rong Li
Qinying Shi
Yannan Xu
Yannan Xu
Ying Lu
Ying Lu
Jianbo Song
author_sort Shihang Li
collection DOAJ
description PurposeTo compare the 3D-printed oral stents (3D-OS) and personalised hand-made stents in dentistry (DentStent) for head and neck malignancies.MethodsTwelve patients with head and neck malignant tumours in the Cancer Centre of Shanxi Bethune Hospital from 1 August 2023 to 31 September 2024 were admitted to the study. After obtaining informed consent from the patients, 3D-OS and DentStent were designed for each patient, respectively, and the patients wore them to produce two groups of radiotherapy plans. The aim was to compare the homogeneity index (HI) and conformity index (CI) of the target areas, as well as the dose differences to the organs at risk (OAR) between the two plans. Additionally, the satisfaction of the patients with the stents after use was assessed.ResultsThe difference in HI, CI and OAR dose to the target area between the two groups was slight, but 3D-OS took less time (∼4 h) to fabricate and resulted in higher resolution and patient satisfaction.ConclusionThe proposed 3D-OS could obtain good HI and CI in radiotherapy for head and neck malignancies, and is a new method for rapid and satisfactory personalised oral stent.
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institution Kabale University
issn 2296-4185
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publishDate 2025-06-01
publisher Frontiers Media S.A.
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series Frontiers in Bioengineering and Biotechnology
spelling doaj-art-4e9b37b0fb2b4668bd2346d0a3cfebbe2025-08-20T03:46:25ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-06-011310.3389/fbioe.2025.15441051544105Comparison of custom-designed oral stents in radiotherapy for head and neck malignanciesShihang Li0Guobao Pang1Rong Li2Rong Li3Qinying Shi4Yannan Xu5Yannan Xu6Ying Lu7Ying Lu8Jianbo Song9Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaShanxi Provincial Key Laboratory for Translational Nuclear Medicine and Precision Protection, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaShanxi Provincial Key Laboratory for Translational Nuclear Medicine and Precision Protection, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaShanxi Provincial Key Laboratory for Translational Nuclear Medicine and Precision Protection, Taiyuan, ChinaCancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaPurposeTo compare the 3D-printed oral stents (3D-OS) and personalised hand-made stents in dentistry (DentStent) for head and neck malignancies.MethodsTwelve patients with head and neck malignant tumours in the Cancer Centre of Shanxi Bethune Hospital from 1 August 2023 to 31 September 2024 were admitted to the study. After obtaining informed consent from the patients, 3D-OS and DentStent were designed for each patient, respectively, and the patients wore them to produce two groups of radiotherapy plans. The aim was to compare the homogeneity index (HI) and conformity index (CI) of the target areas, as well as the dose differences to the organs at risk (OAR) between the two plans. Additionally, the satisfaction of the patients with the stents after use was assessed.ResultsThe difference in HI, CI and OAR dose to the target area between the two groups was slight, but 3D-OS took less time (∼4 h) to fabricate and resulted in higher resolution and patient satisfaction.ConclusionThe proposed 3D-OS could obtain good HI and CI in radiotherapy for head and neck malignancies, and is a new method for rapid and satisfactory personalised oral stent.https://www.frontiersin.org/articles/10.3389/fbioe.2025.1544105/fullhead and neck malignanciesoral stents3D printingradiation doseradiotherapy
spellingShingle Shihang Li
Guobao Pang
Rong Li
Rong Li
Qinying Shi
Yannan Xu
Yannan Xu
Ying Lu
Ying Lu
Jianbo Song
Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
Frontiers in Bioengineering and Biotechnology
head and neck malignancies
oral stents
3D printing
radiation dose
radiotherapy
title Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
title_full Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
title_fullStr Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
title_full_unstemmed Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
title_short Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies
title_sort comparison of custom designed oral stents in radiotherapy for head and neck malignancies
topic head and neck malignancies
oral stents
3D printing
radiation dose
radiotherapy
url https://www.frontiersin.org/articles/10.3389/fbioe.2025.1544105/full
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