Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period
Objective: to study the impact of correcting immune disorders on the course of the disease in patients with abdominal sepsis. Subjects and methods. Ninety-five patients with abdominal sepsis were examined. APACHE III scores were 25—30. Humoral and cellular immunological parameters were studied in al...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2011-02-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/342 |
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| author | E. V. Zilbert S. M Stepanenko I. D. Belyaeva M. I. Fridlyand |
| author_facet | E. V. Zilbert S. M Stepanenko I. D. Belyaeva M. I. Fridlyand |
| author_sort | E. V. Zilbert |
| collection | DOAJ |
| description | Objective: to study the impact of correcting immune disorders on the course of the disease in patients with abdominal sepsis. Subjects and methods. Ninety-five patients with abdominal sepsis were examined. APACHE III scores were 25—30. Humoral and cellular immunological parameters were studied in all the patients. The immunotropic drug Galavit was included into the combination treatment of 42 patients. Results. An immunodeficiency state was found in 74 (80%) patients. The incorporation of targeted immunotherapy into the package of medical measures activated the immune system of patients and, in a number of cases, could elevate the level of T lymphocytes, reduced the rate of laparostomy wound suppurations by 1.9 times and the number of fatal outcomes by 10.1%. Conclusion. Incorporation of targeted immunotherapy into the package of medical measures activates cellular immunity and tissue regeneration processes and reduces the degree of endogenous intoxication, the rate of laparostomy wound suppurations, and the number of fatal outcomes. Key words: abdominal sepsis, immunomodulation, Galavit. |
| format | Article |
| id | doaj-art-4e8d95f8458849be9181bd9b821010cf |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2011-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-4e8d95f8458849be9181bd9b821010cf2025-08-20T02:55:52ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102011-02-017110.15360/1813-9779-2011-1-58342Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative PeriodE. V. ZilbertS. M StepanenkoI. D. BelyaevaM. I. FridlyandObjective: to study the impact of correcting immune disorders on the course of the disease in patients with abdominal sepsis. Subjects and methods. Ninety-five patients with abdominal sepsis were examined. APACHE III scores were 25—30. Humoral and cellular immunological parameters were studied in all the patients. The immunotropic drug Galavit was included into the combination treatment of 42 patients. Results. An immunodeficiency state was found in 74 (80%) patients. The incorporation of targeted immunotherapy into the package of medical measures activated the immune system of patients and, in a number of cases, could elevate the level of T lymphocytes, reduced the rate of laparostomy wound suppurations by 1.9 times and the number of fatal outcomes by 10.1%. Conclusion. Incorporation of targeted immunotherapy into the package of medical measures activates cellular immunity and tissue regeneration processes and reduces the degree of endogenous intoxication, the rate of laparostomy wound suppurations, and the number of fatal outcomes. Key words: abdominal sepsis, immunomodulation, Galavit.https://www.reanimatology.com/rmt/article/view/342 |
| spellingShingle | E. V. Zilbert S. M Stepanenko I. D. Belyaeva M. I. Fridlyand Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period Общая реаниматология |
| title | Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period |
| title_full | Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period |
| title_fullStr | Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period |
| title_full_unstemmed | Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period |
| title_short | Effect of Continuous Promedol Infusion on Recovery of Spontaneous Breathing in Children in the Postoperative Period |
| title_sort | effect of continuous promedol infusion on recovery of spontaneous breathing in children in the postoperative period |
| url | https://www.reanimatology.com/rmt/article/view/342 |
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