RNA-containing extracellular vesicles in infection
Extracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other regulatory RNAs. These RNA types are protected wit...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2024-12-01
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| Series: | RNA Biology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/15476286.2024.2431781 |
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| _version_ | 1850062293379842048 |
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| author | Kayo Schemiko Almeida Suélen Andreia Rossi Lysangela Ronalte Alves |
| author_facet | Kayo Schemiko Almeida Suélen Andreia Rossi Lysangela Ronalte Alves |
| author_sort | Kayo Schemiko Almeida |
| collection | DOAJ |
| description | Extracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other regulatory RNAs. These RNA types are protected within the lipid bilayer of EVs, ensuring their stability and enabling long-distance cellular interactions. Notably, EVs play roles in infection, where pathogens and host cells use EV-mediated RNA transfer to influence immune responses and disease outcomes. For example, bacterial EVs play a crucial role in infection by modulating host immune responses and facilitating pathogen invasion. This review explores the complex interactions between EV-associated RNA and host-pathogen dynamics in bacteria, parasites, and fungi, aiming to uncover molecular mechanisms in infectious diseases and potential therapeutic targets. |
| format | Article |
| id | doaj-art-4e83cf37fd044d78acfa25375dece1f6 |
| institution | DOAJ |
| issn | 1547-6286 1555-8584 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | RNA Biology |
| spelling | doaj-art-4e83cf37fd044d78acfa25375dece1f62025-08-20T02:49:58ZengTaylor & Francis GroupRNA Biology1547-62861555-85842024-12-012111275128910.1080/15476286.2024.2431781RNA-containing extracellular vesicles in infectionKayo Schemiko Almeida0Suélen Andreia Rossi1Lysangela Ronalte Alves2Gene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ, Curitiba, PR, BrazilGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ, Curitiba, PR, BrazilGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ, Curitiba, PR, BrazilExtracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other regulatory RNAs. These RNA types are protected within the lipid bilayer of EVs, ensuring their stability and enabling long-distance cellular interactions. Notably, EVs play roles in infection, where pathogens and host cells use EV-mediated RNA transfer to influence immune responses and disease outcomes. For example, bacterial EVs play a crucial role in infection by modulating host immune responses and facilitating pathogen invasion. This review explores the complex interactions between EV-associated RNA and host-pathogen dynamics in bacteria, parasites, and fungi, aiming to uncover molecular mechanisms in infectious diseases and potential therapeutic targets.https://www.tandfonline.com/doi/10.1080/15476286.2024.2431781Extracellular vesiclesRNAinfectionhost-responsebacteriafungi |
| spellingShingle | Kayo Schemiko Almeida Suélen Andreia Rossi Lysangela Ronalte Alves RNA-containing extracellular vesicles in infection RNA Biology Extracellular vesicles RNA infection host-response bacteria fungi |
| title | RNA-containing extracellular vesicles in infection |
| title_full | RNA-containing extracellular vesicles in infection |
| title_fullStr | RNA-containing extracellular vesicles in infection |
| title_full_unstemmed | RNA-containing extracellular vesicles in infection |
| title_short | RNA-containing extracellular vesicles in infection |
| title_sort | rna containing extracellular vesicles in infection |
| topic | Extracellular vesicles RNA infection host-response bacteria fungi |
| url | https://www.tandfonline.com/doi/10.1080/15476286.2024.2431781 |
| work_keys_str_mv | AT kayoschemikoalmeida rnacontainingextracellularvesiclesininfection AT suelenandreiarossi rnacontainingextracellularvesiclesininfection AT lysangelaronaltealves rnacontainingextracellularvesiclesininfection |