The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity

The purpose is to study the fluorescence angiographic signs of posterior aggressive retinopathy of prematurity. Patients and methods. A prospective study of 83 infants with aggressive posterior retinopathy of prematurity (APROP), who were on treatment in the neonatal center in 2012–2018 years. Gesta...

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Main Authors: E. I. Saidasheva, S. V. Buynovskaya, F. V. Kovshov, Yu. V. Levadnev, O. Y. Shishkanova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2019-04-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/899
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author E. I. Saidasheva
S. V. Buynovskaya
F. V. Kovshov
Yu. V. Levadnev
O. Y. Shishkanova
author_facet E. I. Saidasheva
S. V. Buynovskaya
F. V. Kovshov
Yu. V. Levadnev
O. Y. Shishkanova
author_sort E. I. Saidasheva
collection DOAJ
description The purpose is to study the fluorescence angiographic signs of posterior aggressive retinopathy of prematurity. Patients and methods. A prospective study of 83 infants with aggressive posterior retinopathy of prematurity (APROP), who were on treatment in the neonatal center in 2012–2018 years. Gestational age was between 22 and 30 weeks. Depending on the diagnostic methods, patients were divided into two groups: 1 (main) — 51 (61.4 %) children who, in addition to standard ophthalmic examination methods, received 132 series of FA using a pediatric retinal camera RetCam3; 2 (control) — 32 (38.6 %) children without FA. After the procedure, the somatic state of the child was monitored for 24 hours for the registration of drug dye side effects. Results. Angiographic predictors of the disease and objective signs of APROP manifestation were presented in group 1 children a week earlier than in the group 2. This made laser treatment possible on 2.0 ± 0.5 weeks earlier in the group 1 (32.8 ± 1.2 weeks) compared to group 2 (34.8 ± 1.7 weeks) (p < 0.05) and to increase its efficiency by 8.2 % (86.3 and 78.1 % respectively). Conclusion. Comparative analysis of angiograms and color fundus images obtained with RetCam3 in the studied groups of children demonstrates the advantages and safety FA for the detection angiographic predictors of APROP, early objective signs of disease manifestation, it provides timely and effective laser treatment of complicated categories of very premature infants.
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institution Kabale University
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spelling doaj-art-4e8166e4cc2c4013b5e362b265e1cac72025-08-20T04:00:25ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452019-04-01161S616710.18008/1816-5095-2019-1S-61-67515The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of PrematurityE. I. Saidasheva0S. V. Buynovskaya1F. V. Kovshov2Yu. V. Levadnev3O. Y. Shishkanova4North-Western State Medical University named after I.I. Mechnikov Children’s Hospital No. 1Children’s Hospital No. 1Children’s Hospital No. 1Children’s Hospital No. 1Children’s Hospital No. 1The purpose is to study the fluorescence angiographic signs of posterior aggressive retinopathy of prematurity. Patients and methods. A prospective study of 83 infants with aggressive posterior retinopathy of prematurity (APROP), who were on treatment in the neonatal center in 2012–2018 years. Gestational age was between 22 and 30 weeks. Depending on the diagnostic methods, patients were divided into two groups: 1 (main) — 51 (61.4 %) children who, in addition to standard ophthalmic examination methods, received 132 series of FA using a pediatric retinal camera RetCam3; 2 (control) — 32 (38.6 %) children without FA. After the procedure, the somatic state of the child was monitored for 24 hours for the registration of drug dye side effects. Results. Angiographic predictors of the disease and objective signs of APROP manifestation were presented in group 1 children a week earlier than in the group 2. This made laser treatment possible on 2.0 ± 0.5 weeks earlier in the group 1 (32.8 ± 1.2 weeks) compared to group 2 (34.8 ± 1.7 weeks) (p < 0.05) and to increase its efficiency by 8.2 % (86.3 and 78.1 % respectively). Conclusion. Comparative analysis of angiograms and color fundus images obtained with RetCam3 in the studied groups of children demonstrates the advantages and safety FA for the detection angiographic predictors of APROP, early objective signs of disease manifestation, it provides timely and effective laser treatment of complicated categories of very premature infants.https://www.ophthalmojournal.com/opht/article/view/899aggressive posterior retinopathy of prematurityfluorescein angiographydiagnostic
spellingShingle E. I. Saidasheva
S. V. Buynovskaya
F. V. Kovshov
Yu. V. Levadnev
O. Y. Shishkanova
The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
Oftalʹmologiâ
aggressive posterior retinopathy of prematurity
fluorescein angiography
diagnostic
title The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
title_full The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
title_fullStr The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
title_full_unstemmed The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
title_short The Fluorescein Angiographic Signs of Aggressive Posterior Retinopathy of Prematurity
title_sort fluorescein angiographic signs of aggressive posterior retinopathy of prematurity
topic aggressive posterior retinopathy of prematurity
fluorescein angiography
diagnostic
url https://www.ophthalmojournal.com/opht/article/view/899
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