Inhibition of soluble epoxide hydrolase reverses bone loss in periodontitis by upregulating EMCN and inhibiting osteoclasts

Inhibition of soluble epoxide hydrolase reverses bone loss in periodontitis by upregulating EMCN and inhibiting osteoclasts

Abstract Background Improving the microenvironment to augment endogenous regenerative potential has emerged as a fundamental concept for stimulating and expediting periodontal tissue repair and regeneration. Previous studies have demonstrated that TPPU, a soluble epoxide hydrolase inhibitor (sEHi),...

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Bibliographic Details
Main Authors: Juanjuan Li, Ni Kou, Xiaoli Shi, Lingwenyao Kong, Weixian Chen, Xueping Yang, Yanrong Zhao, Jie Zhao, Fu Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Soluble epoxide hydrolase inhibitor
TPPU
Periodontitis
Tissue regeneration
EMCN
Online Access:https://doi.org/10.1186/s13287-024-04054-y
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