Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant
Purpose: Early diagnosis and treatment of non-alcoholic fatty pancreatic disease (NAFPD) can effectively intervene in the development of type 2 diabetes. This study aimed to evaluate the utility of an improved ultrasound method for diagnosing NAFPD. Methods: All patients underwent abdominal ultrason...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Editorial Office of Advanced Ultrasound in Diagnosis and Therapy
2025-06-01
|
| Series: | Advanced Ultrasound in Diagnosis and Therapy |
| Subjects: | |
| Online Access: | https://www.journaladvancedultrasound.com/fileup/2576-2516/PDF/1751848747154-1320781004.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849427640678612992 |
|---|---|
| author | Lin Jiaojiao, Ke Helin, Xu Shaodan, Xiao Yang, Han Lina, Lyu Guorong, Li Shilin |
| author_facet | Lin Jiaojiao, Ke Helin, Xu Shaodan, Xiao Yang, Han Lina, Lyu Guorong, Li Shilin |
| author_sort | Lin Jiaojiao, Ke Helin, Xu Shaodan, Xiao Yang, Han Lina, Lyu Guorong, Li Shilin |
| collection | DOAJ |
| description | Purpose: Early diagnosis and treatment of non-alcoholic fatty pancreatic disease (NAFPD) can effectively intervene in the development of type 2 diabetes. This study aimed to evaluate the utility of an improved ultrasound method for diagnosing NAFPD. Methods: All patients underwent abdominal ultrasonography (US) and magnetic resonance imaging (MRI) mDixon-Quant technique. Patients with a pancreatic fat fraction (PFF) > 6.2% were in the NAFPD group (NA) and the rest were in the normal group (NC). MRI mDixon-Quant technique was used to evaluate the diagnostic efficiency of NAFPD with improved ultrasound diagnosis. Results: This study included 46 participants. The MRI mDixon-Quant had good repeatability and reproducibility in measuring PFF. The kappa value of the improved version ultrasound (IVUS) method and MRI diagnosis was 0.760 (95% confidence interval [CI] = 0.662-0.858, P < 0.001). That of traditional version ultrasound (TVUS) and MRI diagnosis was 0.497 (P < 0.001). Statistical analyses revealed that pancreatic grading based on both ultrasound evaluation methods correlated with PFF, with IVUS (R2 = 0.812) superior to TVUS (R2 = 0.496). Body weight, body mass index, triglyceride level, abdominal circumference, abdominal visceral fat, total abdominal fat, abdominal visceral fat area, and liver fat content were significantly higher in the NA versus NC group (P < 0.05). Fat fractions of the pancreatic head, body, and tail in the NA group were significantly higher than those in the NC group (P < 0.05). Conclusion: IVUS more consistently predicts NAFPD and correlates better with MRI than TVUS. |
| format | Article |
| id | doaj-art-4e732bf2c2ca468f841db54bc369c474 |
| institution | Kabale University |
| issn | 2576-2516 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Editorial Office of Advanced Ultrasound in Diagnosis and Therapy |
| record_format | Article |
| series | Advanced Ultrasound in Diagnosis and Therapy |
| spelling | doaj-art-4e732bf2c2ca468f841db54bc369c4742025-08-20T03:28:58ZengEditorial Office of Advanced Ultrasound in Diagnosis and TherapyAdvanced Ultrasound in Diagnosis and Therapy2576-25162025-06-019220721410.37015/AUDT.2025.230059Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-QuantLin Jiaojiao, Ke Helin, Xu Shaodan, Xiao Yang, Han Lina, Lyu Guorong, Li Shilin0aDepartment of Ultrasonography, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China;bDepartment of Ultrasonography, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China;cDepartment of Medicine, Quanzhou Medical College, Quanzhou, ChinaPurpose: Early diagnosis and treatment of non-alcoholic fatty pancreatic disease (NAFPD) can effectively intervene in the development of type 2 diabetes. This study aimed to evaluate the utility of an improved ultrasound method for diagnosing NAFPD. Methods: All patients underwent abdominal ultrasonography (US) and magnetic resonance imaging (MRI) mDixon-Quant technique. Patients with a pancreatic fat fraction (PFF) > 6.2% were in the NAFPD group (NA) and the rest were in the normal group (NC). MRI mDixon-Quant technique was used to evaluate the diagnostic efficiency of NAFPD with improved ultrasound diagnosis. Results: This study included 46 participants. The MRI mDixon-Quant had good repeatability and reproducibility in measuring PFF. The kappa value of the improved version ultrasound (IVUS) method and MRI diagnosis was 0.760 (95% confidence interval [CI] = 0.662-0.858, P < 0.001). That of traditional version ultrasound (TVUS) and MRI diagnosis was 0.497 (P < 0.001). Statistical analyses revealed that pancreatic grading based on both ultrasound evaluation methods correlated with PFF, with IVUS (R2 = 0.812) superior to TVUS (R2 = 0.496). Body weight, body mass index, triglyceride level, abdominal circumference, abdominal visceral fat, total abdominal fat, abdominal visceral fat area, and liver fat content were significantly higher in the NA versus NC group (P < 0.05). Fat fractions of the pancreatic head, body, and tail in the NA group were significantly higher than those in the NC group (P < 0.05). Conclusion: IVUS more consistently predicts NAFPD and correlates better with MRI than TVUS.https://www.journaladvancedultrasound.com/fileup/2576-2516/PDF/1751848747154-1320781004.pdf|mri-pdff|ultrasound|pancreatic steatosis |
| spellingShingle | Lin Jiaojiao, Ke Helin, Xu Shaodan, Xiao Yang, Han Lina, Lyu Guorong, Li Shilin Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant Advanced Ultrasound in Diagnosis and Therapy |mri-pdff|ultrasound|pancreatic steatosis |
| title | Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant |
| title_full | Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant |
| title_fullStr | Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant |
| title_full_unstemmed | Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant |
| title_short | Improved Ultrasound Evaluation Method for Diagnosing Nonalcoholic Fatty Pancreatic Disease: Correlation with MRI mDixon-Quant |
| title_sort | improved ultrasound evaluation method for diagnosing nonalcoholic fatty pancreatic disease correlation with mri mdixon quant |
| topic | |mri-pdff|ultrasound|pancreatic steatosis |
| url | https://www.journaladvancedultrasound.com/fileup/2576-2516/PDF/1751848747154-1320781004.pdf |
| work_keys_str_mv | AT linjiaojiaokehelinxushaodanxiaoyanghanlinalyuguoronglishilin improvedultrasoundevaluationmethodfordiagnosingnonalcoholicfattypancreaticdiseasecorrelationwithmrimdixonquant |