Recurrent TRAF7-mutated meningioma: Molecular evolution and therapeutic insights
Meningiomas are the most common primary intracranial tumors, with TRAF7 mutations identified in ~25% of cases. These mutations, associated with NFκB pathway activation, are linked to higher recurrence rates than other low-grade-associated mutations. We report a 49-year-old Caucasian woman with recur...
Saved in:
| Main Authors: | Emily Pack, Sonikpreet Aulakh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2025-08-01
|
| Series: | SAGE Open Medical Case Reports |
| Online Access: | https://doi.org/10.1177/2050313X251363340 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence
by: Yu Chen, et al.
Published: (2025-04-01) -
Different Activation of TRAF4 and TRAF6 in Inflammatory Bowel Disease
by: Jun Shen, et al.
Published: (2013-01-01) -
TRAF3 as a potential diagnostic biomarker for recurrent pregnancy loss: insights from single-cell transcriptomics and machine learning
by: Yi-bo He, et al.
Published: (2025-05-01) -
Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
by: Tsvetana Petrova, et al.
Published: (2022-01-01) -
Impact of molecular genetic profle of meningiomas on the clinical course and recurrence using combined modality treatment
by: G. S. Sergeev, et al.
Published: (2024-01-01)