Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study

Objectives. This study aimed to examine the effect of Ramadan fasting on HbA1c in Muslim patients with type 2 diabetes. The incidence of hypoglycemia and glycemic changes in relation to the adjustment of doses of antidiabetic agents, diet, and physical activity during Ramadan was also evaluated. Met...

Full description

Saved in:
Bibliographic Details
Main Authors: Melanie Yee Lee Siaw, Daniel Ek Kwang Chew, Rinkoo Dalan, Shaikh Abdul Kader Kamaldeen Abdul Shakoor, Noorani Othman, Chor Hui Choo, Nur Hidayah Shamsuri, Siti Nurhana Abdul Karim, Sui Yung Chan, Joyce Yu-Chia Lee
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2014/308546
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549437878042624
author Melanie Yee Lee Siaw
Daniel Ek Kwang Chew
Rinkoo Dalan
Shaikh Abdul Kader Kamaldeen Abdul Shakoor
Noorani Othman
Chor Hui Choo
Nur Hidayah Shamsuri
Siti Nurhana Abdul Karim
Sui Yung Chan
Joyce Yu-Chia Lee
author_facet Melanie Yee Lee Siaw
Daniel Ek Kwang Chew
Rinkoo Dalan
Shaikh Abdul Kader Kamaldeen Abdul Shakoor
Noorani Othman
Chor Hui Choo
Nur Hidayah Shamsuri
Siti Nurhana Abdul Karim
Sui Yung Chan
Joyce Yu-Chia Lee
author_sort Melanie Yee Lee Siaw
collection DOAJ
description Objectives. This study aimed to examine the effect of Ramadan fasting on HbA1c in Muslim patients with type 2 diabetes. The incidence of hypoglycemia and glycemic changes in relation to the adjustment of doses of antidiabetic agents, diet, and physical activity during Ramadan was also evaluated. Methods. This was a prospective study conducted in an outpatient endocrine clinic. A set of questionnaires was administered to Muslim patients with diabetes who fasted for ≥10 days. Those who were hospitalized for diabetic ketoacidosis or severe hypoglycemia a month prior to Ramadan or were given short-term corticosteroid therapy were excluded. The patients’ responses and clinical outcomes from the clinic database were collected before, during, and after Ramadan. Results. A total of 153 participants completed the study. The mean HbA1c improved from 8.9% before Ramadan to 8.6% during Ramadan (P<0.05). Although diet and physical activity did not contribute to changes in glycemia, a significant improvement in HbA1c was observed in patients who had adjustments made to their doses of antidiabetic agents during Ramadan (P<0.001). In addition, their rate of hypoglycemia was minimal. Conclusions. Ramadan fasting appeared to improve glycemic control, especially in those whose doses of antidiabetic agents were adjusted during Ramadan.
format Article
id doaj-art-4e6e07770f054e93a322e130042317cb
institution Kabale University
issn 1687-8337
1687-8345
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series International Journal of Endocrinology
spelling doaj-art-4e6e07770f054e93a322e130042317cb2025-02-03T06:11:13ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/308546308546Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective StudyMelanie Yee Lee Siaw0Daniel Ek Kwang Chew1Rinkoo Dalan2Shaikh Abdul Kader Kamaldeen Abdul Shakoor3Noorani Othman4Chor Hui Choo5Nur Hidayah Shamsuri6Siti Nurhana Abdul Karim7Sui Yung Chan8Joyce Yu-Chia Lee9Department of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, 117543, SingaporeDepartment of Endocrine and Diabetes, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Endocrine and Diabetes, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Endocrine and Diabetes, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Endocrine and Diabetes, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Pharmacy, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, 117543, SingaporeDepartment of Pharmacy, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, 117543, SingaporeDepartment of Pharmacy, Faculty of Science, National University of Singapore, Block S4, 18 Science Drive 4, 117543, SingaporeObjectives. This study aimed to examine the effect of Ramadan fasting on HbA1c in Muslim patients with type 2 diabetes. The incidence of hypoglycemia and glycemic changes in relation to the adjustment of doses of antidiabetic agents, diet, and physical activity during Ramadan was also evaluated. Methods. This was a prospective study conducted in an outpatient endocrine clinic. A set of questionnaires was administered to Muslim patients with diabetes who fasted for ≥10 days. Those who were hospitalized for diabetic ketoacidosis or severe hypoglycemia a month prior to Ramadan or were given short-term corticosteroid therapy were excluded. The patients’ responses and clinical outcomes from the clinic database were collected before, during, and after Ramadan. Results. A total of 153 participants completed the study. The mean HbA1c improved from 8.9% before Ramadan to 8.6% during Ramadan (P<0.05). Although diet and physical activity did not contribute to changes in glycemia, a significant improvement in HbA1c was observed in patients who had adjustments made to their doses of antidiabetic agents during Ramadan (P<0.001). In addition, their rate of hypoglycemia was minimal. Conclusions. Ramadan fasting appeared to improve glycemic control, especially in those whose doses of antidiabetic agents were adjusted during Ramadan.http://dx.doi.org/10.1155/2014/308546
spellingShingle Melanie Yee Lee Siaw
Daniel Ek Kwang Chew
Rinkoo Dalan
Shaikh Abdul Kader Kamaldeen Abdul Shakoor
Noorani Othman
Chor Hui Choo
Nur Hidayah Shamsuri
Siti Nurhana Abdul Karim
Sui Yung Chan
Joyce Yu-Chia Lee
Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
International Journal of Endocrinology
title Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
title_full Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
title_fullStr Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
title_full_unstemmed Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
title_short Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study
title_sort evaluating the effect of ramadan fasting on muslim patients with diabetes in relation to use of medication and lifestyle patterns a prospective study
url http://dx.doi.org/10.1155/2014/308546
work_keys_str_mv AT melanieyeeleesiaw evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT danielekkwangchew evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT rinkoodalan evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT shaikhabdulkaderkamaldeenabdulshakoor evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT nooraniothman evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT chorhuichoo evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT nurhidayahshamsuri evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT sitinurhanaabdulkarim evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT suiyungchan evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy
AT joyceyuchialee evaluatingtheeffectoframadanfastingonmuslimpatientswithdiabetesinrelationtouseofmedicationandlifestylepatternsaprospectivestudy