Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers

Sentinel lymph node dissection (SLND) and biopsy has revolutionized the world of surgical oncology. SLND offers benefits such as decreased risk of lower extremity edema, lower infection rates and reduced blood loss. Many studies have explored the application of SLNB in the context of vulvar and cerv...

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Main Authors: Malavika Perinchery, Kathryn Mills
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578925001110
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author Malavika Perinchery
Kathryn Mills
author_facet Malavika Perinchery
Kathryn Mills
author_sort Malavika Perinchery
collection DOAJ
description Sentinel lymph node dissection (SLND) and biopsy has revolutionized the world of surgical oncology. SLND offers benefits such as decreased risk of lower extremity edema, lower infection rates and reduced blood loss. Many studies have explored the application of SLNB in the context of vulvar and cervical cancers. Evidence has demonstrated that it is a reasonable alternative to complete lymphadenectomy in the appropriate candidate. Furthermore, utilization of different dyes, such as ICG, has resulted in positive outcomes, resulting in shifts in practice. This review explores the current data and best practices for sentinel lymph node mapping and dissection in vulvar and cervical cancers.
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institution Kabale University
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spelling doaj-art-4e6d0df19cae4fc4bc375993e4de643f2025-08-21T04:17:03ZengElsevierGynecologic Oncology Reports2352-57892025-08-016010178610.1016/j.gore.2025.101786Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical CancersMalavika Perinchery0Kathryn Mills1University of Chicago Medical Center, Department of Obstetrics and Gynecology, United States; Corresponding author at: University of Chicago, 5758 S Maryland Ave, Chicago, IL 60637, United States.University of Chicago Medical Center, Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, United StatesSentinel lymph node dissection (SLND) and biopsy has revolutionized the world of surgical oncology. SLND offers benefits such as decreased risk of lower extremity edema, lower infection rates and reduced blood loss. Many studies have explored the application of SLNB in the context of vulvar and cervical cancers. Evidence has demonstrated that it is a reasonable alternative to complete lymphadenectomy in the appropriate candidate. Furthermore, utilization of different dyes, such as ICG, has resulted in positive outcomes, resulting in shifts in practice. This review explores the current data and best practices for sentinel lymph node mapping and dissection in vulvar and cervical cancers.http://www.sciencedirect.com/science/article/pii/S2352578925001110Sentinel lymph node biopsyVulvar cancerCervical cancer
spellingShingle Malavika Perinchery
Kathryn Mills
Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
Gynecologic Oncology Reports
Sentinel lymph node biopsy
Vulvar cancer
Cervical cancer
title Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
title_full Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
title_fullStr Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
title_full_unstemmed Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
title_short Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers
title_sort sentinel decisions current evidence and best practices for lymph node assessment in vulvar and cervical cancers
topic Sentinel lymph node biopsy
Vulvar cancer
Cervical cancer
url http://www.sciencedirect.com/science/article/pii/S2352578925001110
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