Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population

Aims. Much of the diabetes burden is caused by its complications. This cross-sectional study aimed to determine the prevalence and risk factors for diabetic microvascular complications (retinopathy, nephropathy, and neuropathy) in a high-risk population. Methods. We collected information via a struc...

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Main Authors: Sohaila Cheema, Patrick Maisonneuve, Mahmoud Zirie, Amin Jayyousi, Hekmat Alrouh, Amit Abraham, Sura Al-Samraye, Ziyad Mahfoud, Ibrahim Mohammed Al-Janahi, Buthaina Ibrahim, Albert B. Lowenfels, Ravinder Mamtani
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2018/8964027
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author Sohaila Cheema
Patrick Maisonneuve
Mahmoud Zirie
Amin Jayyousi
Hekmat Alrouh
Amit Abraham
Sura Al-Samraye
Ziyad Mahfoud
Ibrahim Mohammed Al-Janahi
Buthaina Ibrahim
Albert B. Lowenfels
Ravinder Mamtani
author_facet Sohaila Cheema
Patrick Maisonneuve
Mahmoud Zirie
Amin Jayyousi
Hekmat Alrouh
Amit Abraham
Sura Al-Samraye
Ziyad Mahfoud
Ibrahim Mohammed Al-Janahi
Buthaina Ibrahim
Albert B. Lowenfels
Ravinder Mamtani
author_sort Sohaila Cheema
collection DOAJ
description Aims. Much of the diabetes burden is caused by its complications. This cross-sectional study aimed to determine the prevalence and risk factors for diabetic microvascular complications (retinopathy, nephropathy, and neuropathy) in a high-risk population. Methods. We collected information via a structured questionnaire and directly from the patient’s record on 1034 adult type 2 diabetic patients who were attending outpatient clinics in Qatar. Results. The mean age of the patients was 55 ± 10 years, and the mean duration of diabetes was 12.4 ± 8.9 years. Forty-five percent had one or more microvascular complications. Shared risk factors for multiplicity and for individual complications included family history, severity and duration of diabetes, and hypertension, but some risk factors were specific for individual microvascular complications. Early age at onset of diabetes was strongly associated with multiplicity of complications (P=0.0003). Conclusions. About half the diabetics in this high-risk population had one or more microvascular complications. Several well-established risk factors were associated with multiplicity and individual microvascular complications, but each separate microvascular complication was linked to a somewhat different constellation of risk factors.
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spelling doaj-art-4e6bb7d8deec46559789e61ac1b210152025-02-03T05:45:39ZengWileyJournal of Diabetes Research2314-67452314-67532018-01-01201810.1155/2018/89640278964027Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East PopulationSohaila Cheema0Patrick Maisonneuve1Mahmoud Zirie2Amin Jayyousi3Hekmat Alrouh4Amit Abraham5Sura Al-Samraye6Ziyad Mahfoud7Ibrahim Mohammed Al-Janahi8Buthaina Ibrahim9Albert B. Lowenfels10Ravinder Mamtani11Institute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarDivision of Epidemiology and Biostatistics, European Institute of Oncology, Milan, ItalyDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarInstitute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarInstitute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarInstitute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarInstitute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarDepartment of Surgery and Department of Family Medicine, New York Medical College, Valhalla, NY, USAInstitute for Population Health, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, P.O. Box 24144, Doha, QatarAims. Much of the diabetes burden is caused by its complications. This cross-sectional study aimed to determine the prevalence and risk factors for diabetic microvascular complications (retinopathy, nephropathy, and neuropathy) in a high-risk population. Methods. We collected information via a structured questionnaire and directly from the patient’s record on 1034 adult type 2 diabetic patients who were attending outpatient clinics in Qatar. Results. The mean age of the patients was 55 ± 10 years, and the mean duration of diabetes was 12.4 ± 8.9 years. Forty-five percent had one or more microvascular complications. Shared risk factors for multiplicity and for individual complications included family history, severity and duration of diabetes, and hypertension, but some risk factors were specific for individual microvascular complications. Early age at onset of diabetes was strongly associated with multiplicity of complications (P=0.0003). Conclusions. About half the diabetics in this high-risk population had one or more microvascular complications. Several well-established risk factors were associated with multiplicity and individual microvascular complications, but each separate microvascular complication was linked to a somewhat different constellation of risk factors.http://dx.doi.org/10.1155/2018/8964027
spellingShingle Sohaila Cheema
Patrick Maisonneuve
Mahmoud Zirie
Amin Jayyousi
Hekmat Alrouh
Amit Abraham
Sura Al-Samraye
Ziyad Mahfoud
Ibrahim Mohammed Al-Janahi
Buthaina Ibrahim
Albert B. Lowenfels
Ravinder Mamtani
Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
Journal of Diabetes Research
title Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
title_full Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
title_fullStr Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
title_full_unstemmed Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
title_short Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population
title_sort risk factors for microvascular complications of diabetes in a high risk middle east population
url http://dx.doi.org/10.1155/2018/8964027
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