A network of conserved damage survival pathways revealed by a genomic RNAi screen.

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

Damage initiates a pleiotropic cellular response aimed at cellular survival when appropriate. To identify genes required for damage survival, we used a cell-based RNAi screen against the Drosophila genome and the alkylating agent methyl methanesulphonate (MMS). Similar studies performed in other mod...

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Bibliographic Details
Main Authors: Dashnamoorthy Ravi, Amy M Wiles, Selvaraj Bhavani, Jianhua Ruan, Philip Leder, Alexander J R Bishop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000527&type=printable
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