Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma

Abstract Neuroinflammation is a significant contributor to the pathology of glaucoma. Targeting key-mediators in this process is a realistic option to slow disease progression. Galectin-3 is a β-galactoside binding lectin that has been associated with inflammation in both systemic and central nervou...

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Bibliographic Details
Main Authors: Anne Rombaut, Rune Brautaset, Pete A. Williams, James R. Tribble
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Brain
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Online Access:https://doi.org/10.1186/s13041-024-01160-z
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