The synthesis and research of the naphthalimide G-quadruplex probe targeting hybrid G4s

The synthesis and research of the naphthalimide G-quadruplex probe targeting hybrid G4s

The human C-MYC promoter and telomere G4 DNA structures were widely recognized as promising targets for cancer therapy. Nevertheless, the effectiveness of the traditional small-molecule fluorescent probe targeting G4 was hindered by limitations in single function and low selectivity, and progress in...

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Bibliographic Details
Main Authors: Lilin Gan, Wenzheng Luo, Qian Cheng, Shanke Wan, Min Wu, Mingqi Wang, Enming Luo, Xianjin Luo, Shuo Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Results in Chemistry
Subjects:
G4 DNA
S phase DNA
Anti-tumor
Fluorescence imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562400701X
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