The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study

Abstract Background In Japan, anticholinergic drugs were contraindicated for glaucoma, regardless of subtype. The contraindication in patients with open-angle glaucoma (OAG) led to excessive medication restrictions because anticholinergic drugs are associated with a low risk of acute glaucoma attack...

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Main Authors: Yukinori Yamada, Tetsuya Murase, Emiko Mashida, Yuki Kakeda, Yuuka Shibata, Hiroaki Matsuo
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Online Access:https://doi.org/10.1186/s40780-025-00414-9
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author Yukinori Yamada
Tetsuya Murase
Emiko Mashida
Yuki Kakeda
Yuuka Shibata
Hiroaki Matsuo
author_facet Yukinori Yamada
Tetsuya Murase
Emiko Mashida
Yuki Kakeda
Yuuka Shibata
Hiroaki Matsuo
author_sort Yukinori Yamada
collection DOAJ
description Abstract Background In Japan, anticholinergic drugs were contraindicated for glaucoma, regardless of subtype. The contraindication in patients with open-angle glaucoma (OAG) led to excessive medication restrictions because anticholinergic drugs are associated with a low risk of acute glaucoma attacks in OAG. To eliminate this problem, the contraindications of anticholinergic drugs were reduced for types from all glaucoma to angle closure glaucoma (ACG) in 2019. This change requires differentiation of OAG from ACG for the proper use of drugs. The Japan Ophthalmologists Association created Glaucoma Information Cards to share glaucoma subtypes and restricted the medication list. However, only a few studies have investigated the efficacy of Glaucoma Information Cards. In this study, we evaluated the benefits of identifying glaucoma subtypes prior to admission by distributing Glaucoma Information Cards to patients through pharmacists. Methods Pharmacists distributed Glaucoma Information Cards to patients whose glaucoma subtype was unclear at the time of the preadmission pharmacist interview and asked them to have the treating ophthalmologist fill out the glaucoma subtype data. We collected patient data, hospitalized clinical department, status of realization of glaucoma subtypes, methods of realization of glaucoma subtypes, and usage of anticholinergic drugs from medical records. Results First, we investigated how hospital pharmacists identify the type of glaucoma. Pharmacists were able to determine the glaucoma type of most patients through medical records, patient interviews, and the Glaucoma Information Card. We analyzed the records of patients who were scheduled for ophthalmology visits prior to admission and had been given Glaucoma Information Cards. Eleven of the 13 patients brought the Glaucoma Information Card to the hospital, which was analyzed by an ophthalmologist. Two patients were administered anticholinergic drugs without restriction because of proven OAG according to the Glaucoma Information Card. One patient was administered cibenzoline for atrial fibrillation. Another patient received isosorbide dinitrate for coronary angiography. These cases indicate that the distribution of Glaucoma Information Cards can help avoid unnecessary medication restrictions in patients with OAG. Conclusions Our results suggest that the distribution of the Glaucoma Information Cards is useful for proper drug use in patients with glaucoma.
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spelling doaj-art-4e54311d72a24786822014e51890d5d72025-02-09T12:47:56ZengBMCJournal of Pharmaceutical Health Care and Sciences2055-02942025-02-011111810.1186/s40780-025-00414-9The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot studyYukinori Yamada0Tetsuya Murase1Emiko Mashida2Yuki Kakeda3Yuuka Shibata4Hiroaki Matsuo5Department of Pharmaceutical Services, Hiroshima University HospitalDepartment of Pharmaceutical Services, Hiroshima University HospitalDepartment of Pharmaceutical Services, Hiroshima University HospitalDepartment of Pharmaceutical Services, Hiroshima University HospitalDepartment of Pharmaceutical Services, Hiroshima University HospitalDepartment of Pharmaceutical Services, Hiroshima University HospitalAbstract Background In Japan, anticholinergic drugs were contraindicated for glaucoma, regardless of subtype. The contraindication in patients with open-angle glaucoma (OAG) led to excessive medication restrictions because anticholinergic drugs are associated with a low risk of acute glaucoma attacks in OAG. To eliminate this problem, the contraindications of anticholinergic drugs were reduced for types from all glaucoma to angle closure glaucoma (ACG) in 2019. This change requires differentiation of OAG from ACG for the proper use of drugs. The Japan Ophthalmologists Association created Glaucoma Information Cards to share glaucoma subtypes and restricted the medication list. However, only a few studies have investigated the efficacy of Glaucoma Information Cards. In this study, we evaluated the benefits of identifying glaucoma subtypes prior to admission by distributing Glaucoma Information Cards to patients through pharmacists. Methods Pharmacists distributed Glaucoma Information Cards to patients whose glaucoma subtype was unclear at the time of the preadmission pharmacist interview and asked them to have the treating ophthalmologist fill out the glaucoma subtype data. We collected patient data, hospitalized clinical department, status of realization of glaucoma subtypes, methods of realization of glaucoma subtypes, and usage of anticholinergic drugs from medical records. Results First, we investigated how hospital pharmacists identify the type of glaucoma. Pharmacists were able to determine the glaucoma type of most patients through medical records, patient interviews, and the Glaucoma Information Card. We analyzed the records of patients who were scheduled for ophthalmology visits prior to admission and had been given Glaucoma Information Cards. Eleven of the 13 patients brought the Glaucoma Information Card to the hospital, which was analyzed by an ophthalmologist. Two patients were administered anticholinergic drugs without restriction because of proven OAG according to the Glaucoma Information Card. One patient was administered cibenzoline for atrial fibrillation. Another patient received isosorbide dinitrate for coronary angiography. These cases indicate that the distribution of Glaucoma Information Cards can help avoid unnecessary medication restrictions in patients with OAG. Conclusions Our results suggest that the distribution of the Glaucoma Information Cards is useful for proper drug use in patients with glaucoma.https://doi.org/10.1186/s40780-025-00414-9Open-angle glaucomaAngle-closure glaucomaAnticholinergic drugProper use
spellingShingle Yukinori Yamada
Tetsuya Murase
Emiko Mashida
Yuki Kakeda
Yuuka Shibata
Hiroaki Matsuo
The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
Journal of Pharmaceutical Health Care and Sciences
Open-angle glaucoma
Angle-closure glaucoma
Anticholinergic drug
Proper use
title The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
title_full The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
title_fullStr The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
title_full_unstemmed The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
title_short The utility of Glaucoma Information Cards for grasping glaucoma subtypes: a single-center pilot study
title_sort utility of glaucoma information cards for grasping glaucoma subtypes a single center pilot study
topic Open-angle glaucoma
Angle-closure glaucoma
Anticholinergic drug
Proper use
url https://doi.org/10.1186/s40780-025-00414-9
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