Insulin Therapy in Diabetic Hyperglycemic Emergencies
<strong>Background:</strong> diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state are two of the most serious metabolic emergencies in diabetic patients. <br /><strong>Objective:</strong> to identify the type of metabolic complications (diabetic ketoaci...
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Universidad de las Ciencias Médicas de Cienfuegos
2014-09-01
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| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/263 |
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| author | Diana Machado Ramírez Manuel Licea Puig |
| author_facet | Diana Machado Ramírez Manuel Licea Puig |
| author_sort | Diana Machado Ramírez |
| collection | DOAJ |
| description | <strong>Background:</strong> diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state are two of the most serious metabolic emergencies in diabetic patients. <br /><strong>Objective:</strong> to identify the type of metabolic complications (diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state) in order to analyze the patients’ outcome considering the plasma pH levels, as well as the mode of insulin administration. <br /><strong>Method:</strong> a cross-sectional descriptive study was conducted in 52 patients admitted to the intensive care unit of the Enrique Cabrera Hospital from 2000 to 2007. The variables analyzed included: type of diabetes mellitus, type of acute complication, mode of insulin administration, blood gas analysis and outcome. <br /><strong>Results:</strong> diabetic ketoacidosis occurred in 57.5 % of the type 1 diabetic patients and in the 42.5 % of the type 2 diabetics. None of the type 1 diabetics developed hyperglycemic hyperosmolar nonketotic state and this complication was observed in 23.0 % of the patients with diabetes type 2. Microdosing was the mode of insulin administration that predominated in both ketoacidosis and hyperglycemic state cases. Mortality was higher in the hyperglycemic state (67 %) and using microdoses in the insulin therapy. <br /><strong>Conclusions:</strong> diabetic ketoacidosis was the major complication. Mortality from diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state was high and the mode of insulin administration was inadequate in some patients. |
| format | Article |
| id | doaj-art-4e4dd1dcbeab415fbbb3bfc7fa2a59f0 |
| institution | Kabale University |
| issn | 2221-2434 |
| language | Spanish |
| publishDate | 2014-09-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj-art-4e4dd1dcbeab415fbbb3bfc7fa2a59f02025-01-30T21:21:57ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342014-09-0143150157181Insulin Therapy in Diabetic Hyperglycemic EmergenciesDiana Machado Ramírez0Manuel Licea Puig1Hospital General Docente Enrique Cabrera. La Habana.Instituto Nacional de Endocrinología. La Habana.<strong>Background:</strong> diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state are two of the most serious metabolic emergencies in diabetic patients. <br /><strong>Objective:</strong> to identify the type of metabolic complications (diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state) in order to analyze the patients’ outcome considering the plasma pH levels, as well as the mode of insulin administration. <br /><strong>Method:</strong> a cross-sectional descriptive study was conducted in 52 patients admitted to the intensive care unit of the Enrique Cabrera Hospital from 2000 to 2007. The variables analyzed included: type of diabetes mellitus, type of acute complication, mode of insulin administration, blood gas analysis and outcome. <br /><strong>Results:</strong> diabetic ketoacidosis occurred in 57.5 % of the type 1 diabetic patients and in the 42.5 % of the type 2 diabetics. None of the type 1 diabetics developed hyperglycemic hyperosmolar nonketotic state and this complication was observed in 23.0 % of the patients with diabetes type 2. Microdosing was the mode of insulin administration that predominated in both ketoacidosis and hyperglycemic state cases. Mortality was higher in the hyperglycemic state (67 %) and using microdoses in the insulin therapy. <br /><strong>Conclusions:</strong> diabetic ketoacidosis was the major complication. Mortality from diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic state was high and the mode of insulin administration was inadequate in some patients.https://revfinlay.sld.cu/index.php/finlay/article/view/263diabetes mellitus tipo iinsulinahiperglucemiacetoacidosis diabéticacoma hiperglucémico hiperosmolar no cetósico |
| spellingShingle | Diana Machado Ramírez Manuel Licea Puig Insulin Therapy in Diabetic Hyperglycemic Emergencies Revista Finlay diabetes mellitus tipo i insulina hiperglucemia cetoacidosis diabética coma hiperglucémico hiperosmolar no cetósico |
| title | Insulin Therapy in Diabetic Hyperglycemic Emergencies |
| title_full | Insulin Therapy in Diabetic Hyperglycemic Emergencies |
| title_fullStr | Insulin Therapy in Diabetic Hyperglycemic Emergencies |
| title_full_unstemmed | Insulin Therapy in Diabetic Hyperglycemic Emergencies |
| title_short | Insulin Therapy in Diabetic Hyperglycemic Emergencies |
| title_sort | insulin therapy in diabetic hyperglycemic emergencies |
| topic | diabetes mellitus tipo i insulina hiperglucemia cetoacidosis diabética coma hiperglucémico hiperosmolar no cetósico |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/263 |
| work_keys_str_mv | AT dianamachadoramirez insulintherapyindiabetichyperglycemicemergencies AT manuelliceapuig insulintherapyindiabetichyperglycemicemergencies |