Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series
Background: Hematological indices such as the neutrophil-lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), and systemic immune inflammation index (SII) have been proposed as markers of inflammatory disease and prognostic indicators in some tumors, but their role remains controversial. This st...
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2025-02-01
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| author | Nestor I. Quiroga Marc Boada Anna Ureña Leandro Grando Xavier Michavila Irene Botias Angela Guirao Irene Bello Rudith Guzman Laureano Molins Ricard Navarro Ricard Ramos |
| author_facet | Nestor I. Quiroga Marc Boada Anna Ureña Leandro Grando Xavier Michavila Irene Botias Angela Guirao Irene Bello Rudith Guzman Laureano Molins Ricard Navarro Ricard Ramos |
| author_sort | Nestor I. Quiroga |
| collection | DOAJ |
| description | Background: Hematological indices such as the neutrophil-lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), and systemic immune inflammation index (SII) have been proposed as markers of inflammatory disease and prognostic indicators in some tumors, but their role remains controversial. This study aims to evaluate the relationship between these indices and postoperative complications in patients undergoing robotic-assisted anatomic lung resection for oncological purposes. Methods: This retrospective, single-center study included patients who underwent anatomical lung resection from January 2022 to June 2023 using robotic-assisted surgery. The data collected included hematological variables, demographic information, body mass index (BMI) data, information about pulmonary function, medical history, postoperative outcomes, and survival data. Results: A total of 96 patients were included, with a median BMI of 26.10. The data distribution across demographic and clinical variables was homogeneous. Univariate and multivariate analyses revealed no significant association between preoperative or postoperative inflammatory indices and postoperative complications, persistent air leak (PAL), or 1-year mortality. Conclusions: This small, retrospective study with short-term follow-up found no significant relationship between inflammatory indices and postoperative outcomes. These findings suggest that SII and similar indices are not reliable predictors of complications, PAL, or mortality in patients undergoing robotic-assisted anatomic lung resection. |
| format | Article |
| id | doaj-art-4e4d49b36e60424d821db6d61137bfd7 |
| institution | DOAJ |
| issn | 2076-3417 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
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| spelling | doaj-art-4e4d49b36e60424d821db6d61137bfd72025-08-20T02:48:09ZengMDPI AGApplied Sciences2076-34172025-02-01153150210.3390/app15031502Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center SeriesNestor I. Quiroga0Marc Boada1Anna Ureña2Leandro Grando3Xavier Michavila4Irene Botias5Angela Guirao6Irene Bello7Rudith Guzman8Laureano Molins9Ricard Navarro10Ricard Ramos11Thoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainInstitut dInvestigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, SpainThoracic Surgery Department, Hospital Clinic, 08036 Barcelona, SpainBackground: Hematological indices such as the neutrophil-lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), and systemic immune inflammation index (SII) have been proposed as markers of inflammatory disease and prognostic indicators in some tumors, but their role remains controversial. This study aims to evaluate the relationship between these indices and postoperative complications in patients undergoing robotic-assisted anatomic lung resection for oncological purposes. Methods: This retrospective, single-center study included patients who underwent anatomical lung resection from January 2022 to June 2023 using robotic-assisted surgery. The data collected included hematological variables, demographic information, body mass index (BMI) data, information about pulmonary function, medical history, postoperative outcomes, and survival data. Results: A total of 96 patients were included, with a median BMI of 26.10. The data distribution across demographic and clinical variables was homogeneous. Univariate and multivariate analyses revealed no significant association between preoperative or postoperative inflammatory indices and postoperative complications, persistent air leak (PAL), or 1-year mortality. Conclusions: This small, retrospective study with short-term follow-up found no significant relationship between inflammatory indices and postoperative outcomes. These findings suggest that SII and similar indices are not reliable predictors of complications, PAL, or mortality in patients undergoing robotic-assisted anatomic lung resection.https://www.mdpi.com/2076-3417/15/3/1502scoresrobotic surgerySIIprognosticlung resectioninflammation |
| spellingShingle | Nestor I. Quiroga Marc Boada Anna Ureña Leandro Grando Xavier Michavila Irene Botias Angela Guirao Irene Bello Rudith Guzman Laureano Molins Ricard Navarro Ricard Ramos Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series Applied Sciences scores robotic surgery SII prognostic lung resection inflammation |
| title | Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series |
| title_full | Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series |
| title_fullStr | Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series |
| title_full_unstemmed | Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series |
| title_short | Peripheral Blood-Derived Inflammatory Indices Are Not Predictors for Complications in Robotic Thoracic Lung Cancer Surgery: A Retrospective Single-Center Series |
| title_sort | peripheral blood derived inflammatory indices are not predictors for complications in robotic thoracic lung cancer surgery a retrospective single center series |
| topic | scores robotic surgery SII prognostic lung resection inflammation |
| url | https://www.mdpi.com/2076-3417/15/3/1502 |
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