Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation
There are numerous evaluations of natural products, of which majority are food bioactives, performed up to date for their various health beneficial activities via targeting specific proteins. However, the direct identification of a targeted protein remains unexplored for natural occurring compounds....
Saved in:
| Main Authors: | Guliang Yang, Haiyan Zhong, Xinxin Xia, Zhiwen Qi, Chengzhang Wang, Shiming Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2022-03-01
|
| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453021000951 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Oligonucleotide-based PROTACs to Degrade RNA- and DNA-Binding Proteins
by: Céline N. Weller, et al.
Published: (2025-03-01) -
PROTAC Technology as a New Tool for Modern Pharmacotherapy
by: Natalia Kubryń, et al.
Published: (2025-05-01) -
Advancing Design Strategy of PROTACs for Cancer Therapy
by: Hang Luo, et al.
Published: (2025-07-01) -
Preparation and Characterization of Ternary Complexes to Improve the Solubility and Dissolution Performance of a Proteolysis-Targeting Chimera Drug
by: Heng Zhang, et al.
Published: (2025-05-01) -
Targeting METTL3 protein by proteolysis-targeting chimeras: A novel therapeutic approach for acute myeloid leukemia
by: Rukiye Nar, et al.
Published: (2025-07-01)