Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains

In the industrial production of <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i>, slow growth of the mother seed and insufficient hyphal vitality can significantly affect the cultivation process. To shorten the growth period on traditional PDA medium, two strains of <i...

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Main Authors: Zhanghu Chen, Ruiheng Yang, Yan Li, Lihua Tang, Huiyang Xiong, Dapeng Bao, Ting Guo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Fungi
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Online Access:https://www.mdpi.com/2309-608X/10/12/808
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author Zhanghu Chen
Ruiheng Yang
Yan Li
Lihua Tang
Huiyang Xiong
Dapeng Bao
Ting Guo
author_facet Zhanghu Chen
Ruiheng Yang
Yan Li
Lihua Tang
Huiyang Xiong
Dapeng Bao
Ting Guo
author_sort Zhanghu Chen
collection DOAJ
description In the industrial production of <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i>, slow growth of the mother seed and insufficient hyphal vitality can significantly affect the cultivation process. To shorten the growth period on traditional PDA medium, two strains of <i>L. edodes</i> and <i>P. eryngii</i> were cultured with different proportions of <i>P</i>. <i>tuber-regium</i> and <i>Wolfiporia hoelen</i> sclerotium powders added into the medium to investigate the effect on the mycelial growth. Compared to the PDA, the addition of sclerotia powder significantly enhanced the growth of mycelia, with an optimal addition ratio of 2%. Transcriptome sequencing was performed after culturing <i>L. edodes</i> and <i>P. eryngii</i> on PDA, PDA with 2% <i>P. tuber-regium</i> sclerotium powder, and PDA with 2% <i>W. hoelen</i> sclerotium powder. GO enrichment analysis of the differentially expressed genes (DEGs) of <i>L. edodes</i> and <i>P. eryngii</i> strains cultured in the sclerotia powder media showed significant changes in oxidoreductase and glucosidase activities. Changes were observed in KEGG annotation for carbohydrate metabolism, glycolysis, pyruvate metabolism, and other energy metabolic pathways. Moreover, carbohydrate-active enzyme (CAZyme) family genes were predominantly upregulated. The increase in the activity of CAZyme and oxidoreductases promotes the degradation of nutrients in the sclerotia into small-molecule substances, which explains why the sclerotia powder culture medium promotes mycelial growth.
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spelling doaj-art-4e34d4fb10e44396bdfcfb1d8c03af3a2025-08-20T02:56:59ZengMDPI AGJournal of Fungi2309-608X2024-11-01101280810.3390/jof10120808Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> StrainsZhanghu Chen0Ruiheng Yang1Yan Li2Lihua Tang3Huiyang Xiong4Dapeng Bao5Ting Guo6National Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaNational Research Center for Edible Fungi Biotechnology and Engineering, Key Laboratory of Applied Mycological Resources and Utilization, Ministry of Agriculture, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, ChinaIn the industrial production of <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i>, slow growth of the mother seed and insufficient hyphal vitality can significantly affect the cultivation process. To shorten the growth period on traditional PDA medium, two strains of <i>L. edodes</i> and <i>P. eryngii</i> were cultured with different proportions of <i>P</i>. <i>tuber-regium</i> and <i>Wolfiporia hoelen</i> sclerotium powders added into the medium to investigate the effect on the mycelial growth. Compared to the PDA, the addition of sclerotia powder significantly enhanced the growth of mycelia, with an optimal addition ratio of 2%. Transcriptome sequencing was performed after culturing <i>L. edodes</i> and <i>P. eryngii</i> on PDA, PDA with 2% <i>P. tuber-regium</i> sclerotium powder, and PDA with 2% <i>W. hoelen</i> sclerotium powder. GO enrichment analysis of the differentially expressed genes (DEGs) of <i>L. edodes</i> and <i>P. eryngii</i> strains cultured in the sclerotia powder media showed significant changes in oxidoreductase and glucosidase activities. Changes were observed in KEGG annotation for carbohydrate metabolism, glycolysis, pyruvate metabolism, and other energy metabolic pathways. Moreover, carbohydrate-active enzyme (CAZyme) family genes were predominantly upregulated. The increase in the activity of CAZyme and oxidoreductases promotes the degradation of nutrients in the sclerotia into small-molecule substances, which explains why the sclerotia powder culture medium promotes mycelial growth.https://www.mdpi.com/2309-608X/10/12/808<i>Lentinula edodes</i><i>Pleurotus eryngii</i>sclerotiumtranscriptomemedium compositionenergy metabolism
spellingShingle Zhanghu Chen
Ruiheng Yang
Yan Li
Lihua Tang
Huiyang Xiong
Dapeng Bao
Ting Guo
Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
Journal of Fungi
<i>Lentinula edodes</i>
<i>Pleurotus eryngii</i>
sclerotium
transcriptome
medium composition
energy metabolism
title Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
title_full Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
title_fullStr Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
title_full_unstemmed Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
title_short Transcriptome Analysis of the Growth-Promoting Effect of Large Macrofungal Sclerotium Powder on <i>Lentinula edodes</i> and <i>Pleurotus eryngii</i> Strains
title_sort transcriptome analysis of the growth promoting effect of large macrofungal sclerotium powder on i lentinula edodes i and i pleurotus eryngii i strains
topic <i>Lentinula edodes</i>
<i>Pleurotus eryngii</i>
sclerotium
transcriptome
medium composition
energy metabolism
url https://www.mdpi.com/2309-608X/10/12/808
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