Clinical spectrum and management of anterior scleritis: case reports

Scleritis is a rare, potentially sight-threatening, painful eye disease. Based on its anatomical involvement, it can be categorized as anterior and posterior scleritis. There are several possible causes, among which infectious and noninfectious origins should be considered. From the therapeutic aspe...

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Main Authors: Dominika Ördögh, Lilla Smeller, Dóra Júlia Szabó, Nicolette Sohár
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Therapeutic Advances in Ophthalmology
Online Access:https://doi.org/10.1177/25158414251356374
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author Dominika Ördögh
Lilla Smeller
Dóra Júlia Szabó
Nicolette Sohár
author_facet Dominika Ördögh
Lilla Smeller
Dóra Júlia Szabó
Nicolette Sohár
author_sort Dominika Ördögh
collection DOAJ
description Scleritis is a rare, potentially sight-threatening, painful eye disease. Based on its anatomical involvement, it can be categorized as anterior and posterior scleritis. There are several possible causes, among which infectious and noninfectious origins should be considered. From the therapeutic aspect, it is important to clarify the infectious origin, to provide target treatment, or to identify the possible underlying autoimmune disease. Corticosteroid therapy is considered to be the basis for the stepwise treatment of scleritis. In this article, we describe the management of three patients (investigations, stepwise approach of therapy, and treatment difficulties) who developed three different types of scleritis: anterior non-necrotizing scleritis, anterior necrotizing scleritis, and scleromalacia perforans. The differential diagnosis of scleritis and its management after diagnosis pose difficulties in clinical practice. In general, the therapeutic approach is based on the principle of early and individualized treatment, which depends on the nature and severity of the patient’s inflammatory eye disease and the presence or absence of associated systemic diseases.
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institution Kabale University
issn 2515-8414
language English
publishDate 2025-08-01
publisher SAGE Publishing
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series Therapeutic Advances in Ophthalmology
spelling doaj-art-4e34b1d533c34ec69c8165e9ed70e5892025-08-20T03:36:42ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142025-08-011710.1177/25158414251356374Clinical spectrum and management of anterior scleritis: case reportsDominika ÖrdöghLilla SmellerDóra Júlia SzabóNicolette SohárScleritis is a rare, potentially sight-threatening, painful eye disease. Based on its anatomical involvement, it can be categorized as anterior and posterior scleritis. There are several possible causes, among which infectious and noninfectious origins should be considered. From the therapeutic aspect, it is important to clarify the infectious origin, to provide target treatment, or to identify the possible underlying autoimmune disease. Corticosteroid therapy is considered to be the basis for the stepwise treatment of scleritis. In this article, we describe the management of three patients (investigations, stepwise approach of therapy, and treatment difficulties) who developed three different types of scleritis: anterior non-necrotizing scleritis, anterior necrotizing scleritis, and scleromalacia perforans. The differential diagnosis of scleritis and its management after diagnosis pose difficulties in clinical practice. In general, the therapeutic approach is based on the principle of early and individualized treatment, which depends on the nature and severity of the patient’s inflammatory eye disease and the presence or absence of associated systemic diseases.https://doi.org/10.1177/25158414251356374
spellingShingle Dominika Ördögh
Lilla Smeller
Dóra Júlia Szabó
Nicolette Sohár
Clinical spectrum and management of anterior scleritis: case reports
Therapeutic Advances in Ophthalmology
title Clinical spectrum and management of anterior scleritis: case reports
title_full Clinical spectrum and management of anterior scleritis: case reports
title_fullStr Clinical spectrum and management of anterior scleritis: case reports
title_full_unstemmed Clinical spectrum and management of anterior scleritis: case reports
title_short Clinical spectrum and management of anterior scleritis: case reports
title_sort clinical spectrum and management of anterior scleritis case reports
url https://doi.org/10.1177/25158414251356374
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