Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report
We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regime...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2012/787305 |
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| author | K. Grabmeier-Pfistershammer W. Poeppl P. M. Brunner K. Rappersberger A. Rieger |
| author_facet | K. Grabmeier-Pfistershammer W. Poeppl P. M. Brunner K. Rappersberger A. Rieger |
| author_sort | K. Grabmeier-Pfistershammer |
| collection | DOAJ |
| description | We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regimens including liposomal amphotericin B, liposomal amphotericin B with miltefosine, liposomal amphotericin B with interferon, and pentamidine combined fluconazole and allopurinol were applied until Leishmania PCR from blood turned negative. This case supports the necessity of multidrug combinational and sequential therapy over a very prolonged period of time in severely immunosuppressed patients infected with Leishmania and highlights the tremendous individual but also economic burden of this disease. |
| format | Article |
| id | doaj-art-4e2ec3db45c24af7b1cfdf5ed2e9ea72 |
| institution | DOAJ |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-4e2ec3db45c24af7b1cfdf5ed2e9ea722025-08-20T03:19:32ZengWileyCase Reports in Infectious Diseases2090-66252090-66332012-01-01201210.1155/2012/787305787305Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case ReportK. Grabmeier-Pfistershammer0W. Poeppl1P. M. Brunner2K. Rappersberger3A. Rieger4Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Infectious Diseases and Tropical Medicine, Medical University of Vienna, 1090 Vienna, AustriaDivision of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Dermatology and Venereology, Rudolfstiftung Hospital, 1030 Vienna, AustriaDivision of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, 1090 Vienna, AustriaWe report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regimens including liposomal amphotericin B, liposomal amphotericin B with miltefosine, liposomal amphotericin B with interferon, and pentamidine combined fluconazole and allopurinol were applied until Leishmania PCR from blood turned negative. This case supports the necessity of multidrug combinational and sequential therapy over a very prolonged period of time in severely immunosuppressed patients infected with Leishmania and highlights the tremendous individual but also economic burden of this disease.http://dx.doi.org/10.1155/2012/787305 |
| spellingShingle | K. Grabmeier-Pfistershammer W. Poeppl P. M. Brunner K. Rappersberger A. Rieger Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report Case Reports in Infectious Diseases |
| title | Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report |
| title_full | Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report |
| title_fullStr | Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report |
| title_full_unstemmed | Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report |
| title_short | Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report |
| title_sort | clinical challenges in the management of leishmania hiv coinfection in a nonendemic area a case report |
| url | http://dx.doi.org/10.1155/2012/787305 |
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