Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes
<b>Background/Objectives</b>: Vacuum-assisted excision (VAE) is a minimally invasive technique for breast tumor treatment, offering precision, comfort, and quick recovery. It is widely used for benign breast lesions and is playing an increasingly important role in the therapeutic managem...
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MDPI AG
2025-01-01
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| author | Serena Carriero Maurizio Cè Matilde Pavan Mariassunta Roberta Pannarale Giulia Quercioli Sveva Mortellaro Alessandro Liguori Maria Cosentino Maria Iodice Marta Montesano Giulia Querques Carolina Lanza Salvatore Alessio Angileri Pierpaolo Biondetti Filippo Pesapane Gianpaolo Carrafiello Sonia Santicchia |
| author_facet | Serena Carriero Maurizio Cè Matilde Pavan Mariassunta Roberta Pannarale Giulia Quercioli Sveva Mortellaro Alessandro Liguori Maria Cosentino Maria Iodice Marta Montesano Giulia Querques Carolina Lanza Salvatore Alessio Angileri Pierpaolo Biondetti Filippo Pesapane Gianpaolo Carrafiello Sonia Santicchia |
| author_sort | Serena Carriero |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: Vacuum-assisted excision (VAE) is a minimally invasive technique for breast tumor treatment, offering precision, comfort, and quick recovery. It is widely used for benign breast lesions and is playing an increasingly important role in the therapeutic management of non-surgical patients or patients who refuse surgery. Optimal outcomes require an understanding of device features to tailor treatment to each lesion. The Mammotome<sup>®</sup> Elite 10G operates in a fixed mode, while the Mammotome<sup>®</sup> Revolve EX 8G offers multiple aspiration levels and aperture windows for greater versatility. This study analyzed the specimen features (weight and length), comparing the weight obtained from two different VAE systems to aid the appropriate selection of a device based on the clinical setting. It also determined the number of specimens needed to achieve the 4 g diagnostic threshold. <b>Methods</b>: The Mammotome<sup>®</sup> Elite 10G and the Mammotome<sup>®</sup> Revolve EX were evaluated under controlled conditions. For Mammotome<sup>®</sup> Revolve EX, combinations of five aspiration levels and three aperture lengths (12 mm, 18 mm, and 25 mm) were tested. Twelve samples were collected from a chicken breast phantom for each setting. Specimen weights and the minimum excisions required to reach the 4 g threshold were analyzed. <b>Results</b>: The mean weight per sample for the Mammotome<sup>®</sup> Elite 10G was 0.16 ± 0.04 g. For the Mammotome<sup>®</sup> Revolve EX, the weights increased with aperture size and aspiration level, ranging from a minimum of 0.132 ± 0.028 g (a window length of 12 mm and aspiration level 1) to a maximum of 0.407 ± 0.055 g (a window length of 25 mm and aspiration level 5). The 25 mm window at aspiration level 5 achieved the 4 g threshold in as few as 10 samples. By comparison, the Mammotome<sup>®</sup> Elite required up to 26 samples. <b>Conclusions</b>: Compared to the Mammotome Elite, Mammotome<sup>®</sup> Revolve EX offers superior versatility and efficiency, reducing patient discomfort by minimizing the required samples. Its technical advantages make it a valuable tool for both diagnostic and therapeutic applications. |
| format | Article |
| id | doaj-art-4e28ac5b20d440cd87caa8fd0678516e |
| institution | OA Journals |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-4e28ac5b20d440cd87caa8fd0678516e2025-08-20T02:12:24ZengMDPI AGDiagnostics2075-44182025-01-0115327210.3390/diagnostics15030272Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window SizesSerena Carriero0Maurizio Cè1Matilde Pavan2Mariassunta Roberta Pannarale3Giulia Quercioli4Sveva Mortellaro5Alessandro Liguori6Maria Cosentino7Maria Iodice8Marta Montesano9Giulia Querques10Carolina Lanza11Salvatore Alessio Angileri12Pierpaolo Biondetti13Filippo Pesapane14Gianpaolo Carrafiello15Sonia Santicchia16Radiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, ItalyPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, ItalyPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, ItalyPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, ItalyPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Via Festa del Perdono 7, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyBreast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, ItalyRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy<b>Background/Objectives</b>: Vacuum-assisted excision (VAE) is a minimally invasive technique for breast tumor treatment, offering precision, comfort, and quick recovery. It is widely used for benign breast lesions and is playing an increasingly important role in the therapeutic management of non-surgical patients or patients who refuse surgery. Optimal outcomes require an understanding of device features to tailor treatment to each lesion. The Mammotome<sup>®</sup> Elite 10G operates in a fixed mode, while the Mammotome<sup>®</sup> Revolve EX 8G offers multiple aspiration levels and aperture windows for greater versatility. This study analyzed the specimen features (weight and length), comparing the weight obtained from two different VAE systems to aid the appropriate selection of a device based on the clinical setting. It also determined the number of specimens needed to achieve the 4 g diagnostic threshold. <b>Methods</b>: The Mammotome<sup>®</sup> Elite 10G and the Mammotome<sup>®</sup> Revolve EX were evaluated under controlled conditions. For Mammotome<sup>®</sup> Revolve EX, combinations of five aspiration levels and three aperture lengths (12 mm, 18 mm, and 25 mm) were tested. Twelve samples were collected from a chicken breast phantom for each setting. Specimen weights and the minimum excisions required to reach the 4 g threshold were analyzed. <b>Results</b>: The mean weight per sample for the Mammotome<sup>®</sup> Elite 10G was 0.16 ± 0.04 g. For the Mammotome<sup>®</sup> Revolve EX, the weights increased with aperture size and aspiration level, ranging from a minimum of 0.132 ± 0.028 g (a window length of 12 mm and aspiration level 1) to a maximum of 0.407 ± 0.055 g (a window length of 25 mm and aspiration level 5). The 25 mm window at aspiration level 5 achieved the 4 g threshold in as few as 10 samples. By comparison, the Mammotome<sup>®</sup> Elite required up to 26 samples. <b>Conclusions</b>: Compared to the Mammotome Elite, Mammotome<sup>®</sup> Revolve EX offers superior versatility and efficiency, reducing patient discomfort by minimizing the required samples. Its technical advantages make it a valuable tool for both diagnostic and therapeutic applications.https://www.mdpi.com/2075-4418/15/3/272breastsample volumevacuum-assisted biopsyvacuum-assisted excisionbreast cancerbreast benign lesions |
| spellingShingle | Serena Carriero Maurizio Cè Matilde Pavan Mariassunta Roberta Pannarale Giulia Quercioli Sveva Mortellaro Alessandro Liguori Maria Cosentino Maria Iodice Marta Montesano Giulia Querques Carolina Lanza Salvatore Alessio Angileri Pierpaolo Biondetti Filippo Pesapane Gianpaolo Carrafiello Sonia Santicchia Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes Diagnostics breast sample volume vacuum-assisted biopsy vacuum-assisted excision breast cancer breast benign lesions |
| title | Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes |
| title_full | Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes |
| title_fullStr | Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes |
| title_full_unstemmed | Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes |
| title_short | Ultrasound-Guided Vacuum-Assisted Excision (VAE) in Breast Lesion Management: An Experimental Comparative Study of Two Different VAE Devices Across Various Aspiration Levels and Window Sizes |
| title_sort | ultrasound guided vacuum assisted excision vae in breast lesion management an experimental comparative study of two different vae devices across various aspiration levels and window sizes |
| topic | breast sample volume vacuum-assisted biopsy vacuum-assisted excision breast cancer breast benign lesions |
| url | https://www.mdpi.com/2075-4418/15/3/272 |
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