Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment

Purpose: To evaluate the prevalence, related risk factors, treatment and follow-up results in cases of retinopathy of prematurity (ROP). Material and Method: Medical records of 405 premature infants who attended our clinic between August 1999 and September 2004 were retrospectively screened. Amon...

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Main Authors: Sibel Kocabeyo¤lu, Sibel Kaday›fc›lar, Bora Eldem
Format: Article
Language:English
Published: Galenos Publishing House 2011-06-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/article_1349/Retinopathy-Of-Prematurity-Risk-Factors-Prognosis-And-Treatment
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author Sibel Kocabeyo¤lu
Sibel Kaday›fc›lar
Bora Eldem
author_facet Sibel Kocabeyo¤lu
Sibel Kaday›fc›lar
Bora Eldem
author_sort Sibel Kocabeyo¤lu
collection DOAJ
description Purpose: To evaluate the prevalence, related risk factors, treatment and follow-up results in cases of retinopathy of prematurity (ROP). Material and Method: Medical records of 405 premature infants who attended our clinic between August 1999 and September 2004 were retrospectively screened. Among these patients, 379 infants were followed up in our neonatology unit and 26 were referred to us from other clinics. Indirect diode laser photocoagulation and/or cryotherapy were performed when prethreshold or threshold ROP was detected. Surgery was performed in stage IV-V ROP. Results: ROP was detected in 88 out of 405 infants (21.72%). At the first examination, stage I ROP was detected in 18 eyes (10.4%), stage II - in 67 eyes (38.72%), stage III - in 82 eyes (47.39%), and stage IV-V – in 6 eyes (3.46%). Indirect diode laser photocoagulation was applied to 34 eyes with stage II and in 47 eyes with stage III ROP. Ten eyes with threshold ROP and 4 eyes which progressed to threshold ROP were treated with cryotherapy. Scleral buckling was performed in 3 eyes that progressed to stage IV ROP. At the first examination, 2 eyes with stage IV-V ROP were treated with pars plana vitrectomy (PPV). Discussion: In our series, the most important risk factors for development and progression of ROP were found to be low birth weight, low gestational age, mechanical ventilation and multiple pregnancy. Effective screening, follow-up and appropriate treatment are important for prevention of permanent damage and unfavorable outcome in ROP. (Turk J Ophthalmol 2011; 41: 128-32
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issn 1300-0659
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publishDate 2011-06-01
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series Türk Oftalmoloji Dergisi
spelling doaj-art-4e278bb50eaa4302b6cfeace8b2dc9e32025-08-20T03:36:41ZengGalenos Publishing HouseTürk Oftalmoloji Dergisi1300-06592147-26612011-06-0141312813210.4274/tjo.41.479550Retinopathy of Prematurity; Risk Factors, Prognosis and TreatmentSibel Kocabeyo¤lu0Sibel Kaday›fc›lar1Bora Eldem 2Hacettepe Üniversitesi T›p Fakültesi, Göz Hastal›klar› Anabilim Dal›, Ankara, TürkiyeHacettepe Üniversitesi T›p Fakültesi, Göz Hastal›klar› Anabilim Dal›, Ankara, TürkiyeHacettepe Üniversitesi T›p Fakültesi, Göz Hastal›klar› Anabilim Dal›, Ankara, TürkiyePurpose: To evaluate the prevalence, related risk factors, treatment and follow-up results in cases of retinopathy of prematurity (ROP). Material and Method: Medical records of 405 premature infants who attended our clinic between August 1999 and September 2004 were retrospectively screened. Among these patients, 379 infants were followed up in our neonatology unit and 26 were referred to us from other clinics. Indirect diode laser photocoagulation and/or cryotherapy were performed when prethreshold or threshold ROP was detected. Surgery was performed in stage IV-V ROP. Results: ROP was detected in 88 out of 405 infants (21.72%). At the first examination, stage I ROP was detected in 18 eyes (10.4%), stage II - in 67 eyes (38.72%), stage III - in 82 eyes (47.39%), and stage IV-V – in 6 eyes (3.46%). Indirect diode laser photocoagulation was applied to 34 eyes with stage II and in 47 eyes with stage III ROP. Ten eyes with threshold ROP and 4 eyes which progressed to threshold ROP were treated with cryotherapy. Scleral buckling was performed in 3 eyes that progressed to stage IV ROP. At the first examination, 2 eyes with stage IV-V ROP were treated with pars plana vitrectomy (PPV). Discussion: In our series, the most important risk factors for development and progression of ROP were found to be low birth weight, low gestational age, mechanical ventilation and multiple pregnancy. Effective screening, follow-up and appropriate treatment are important for prevention of permanent damage and unfavorable outcome in ROP. (Turk J Ophthalmol 2011; 41: 128-32http://www.oftalmoloji.org/article_1349/Retinopathy-Of-Prematurity-Risk-Factors-Prognosis-And-TreatmentRetinopathy of prematuritylow birth weightlow gestational age
spellingShingle Sibel Kocabeyo¤lu
Sibel Kaday›fc›lar
Bora Eldem
Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
Türk Oftalmoloji Dergisi
Retinopathy of prematurity
low birth weight
low gestational age
title Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
title_full Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
title_fullStr Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
title_full_unstemmed Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
title_short Retinopathy of Prematurity; Risk Factors, Prognosis and Treatment
title_sort retinopathy of prematurity risk factors prognosis and treatment
topic Retinopathy of prematurity
low birth weight
low gestational age
url http://www.oftalmoloji.org/article_1349/Retinopathy-Of-Prematurity-Risk-Factors-Prognosis-And-Treatment
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AT sibelkadayfclar retinopathyofprematurityriskfactorsprognosisandtreatment
AT boraeldem retinopathyofprematurityriskfactorsprognosisandtreatment