Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report

Small-cell lung carcinoma (SCLC) associated with cystic airspaces is rare. We describe the case of a 68-year-old man who was referred to our hospital because of a cystic lesion detected on chest radiography. Initial computed tomography revealed a small nodule abutting the cystic airspace due to para...

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Main Authors: Hirokazu Touge, Haruki Masui, Mitsuhiro Yamamoto, Tomoyuki Ikeuchi, Tomohiro Sakamoto, Katsuyuki Tomita, Akira Yamasaki
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/carm/5314337
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author Hirokazu Touge
Haruki Masui
Mitsuhiro Yamamoto
Tomoyuki Ikeuchi
Tomohiro Sakamoto
Katsuyuki Tomita
Akira Yamasaki
author_facet Hirokazu Touge
Haruki Masui
Mitsuhiro Yamamoto
Tomoyuki Ikeuchi
Tomohiro Sakamoto
Katsuyuki Tomita
Akira Yamasaki
author_sort Hirokazu Touge
collection DOAJ
description Small-cell lung carcinoma (SCLC) associated with cystic airspaces is rare. We describe the case of a 68-year-old man who was referred to our hospital because of a cystic lesion detected on chest radiography. Initial computed tomography revealed a small nodule abutting the cystic airspace due to paraseptal emphysema in the right lower lobe. Histopathological examination of lymphadenopathy indicated SCLC. Postchemotherapy, recurrence appeared as a thick-walled cystic airspace with an exophytic nodule along the cyst wall, mimicking pneumonia. Additional chemotherapy, but not antibiotic therapy, led to a reduction in the wall thickness and nodules. This case emphasizes unresponsiveness to antibiotic therapy, especially in patients with risk factors, highlighting the diagnostic pitfall that may delay timely cancer treatment.
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institution DOAJ
issn 1687-9635
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publishDate 2025-01-01
publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-4e242f7c5c5d40b4854dcccf23adddf92025-08-20T03:09:08ZengWileyCase Reports in Medicine1687-96352025-01-01202510.1155/carm/5314337Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case ReportHirokazu Touge0Haruki Masui1Mitsuhiro Yamamoto2Tomoyuki Ikeuchi3Tomohiro Sakamoto4Katsuyuki Tomita5Akira Yamasaki6Department of Respiratory MedicineCenter for Clinical Residency ProgramDepartment of Respiratory MedicineDepartment of Respiratory MedicineDivision of Respiratory Medicine and RheumatologyDepartment of Respiratory MedicineDivision of Respiratory Medicine and RheumatologySmall-cell lung carcinoma (SCLC) associated with cystic airspaces is rare. We describe the case of a 68-year-old man who was referred to our hospital because of a cystic lesion detected on chest radiography. Initial computed tomography revealed a small nodule abutting the cystic airspace due to paraseptal emphysema in the right lower lobe. Histopathological examination of lymphadenopathy indicated SCLC. Postchemotherapy, recurrence appeared as a thick-walled cystic airspace with an exophytic nodule along the cyst wall, mimicking pneumonia. Additional chemotherapy, but not antibiotic therapy, led to a reduction in the wall thickness and nodules. This case emphasizes unresponsiveness to antibiotic therapy, especially in patients with risk factors, highlighting the diagnostic pitfall that may delay timely cancer treatment.http://dx.doi.org/10.1155/carm/5314337
spellingShingle Hirokazu Touge
Haruki Masui
Mitsuhiro Yamamoto
Tomoyuki Ikeuchi
Tomohiro Sakamoto
Katsuyuki Tomita
Akira Yamasaki
Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
Case Reports in Medicine
title Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
title_full Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
title_fullStr Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
title_full_unstemmed Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
title_short Small-Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report
title_sort small cell lung carcinoma associated with cystic airspaces a case report
url http://dx.doi.org/10.1155/carm/5314337
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