Neoantigen-based mRNA vaccine exhibits superior anti-tumor activity compared to synthetic long peptides in an in vivo lung carcinoma model
Abstract Neoantigen vaccines hold great promise in cancer immunotherapy, but the comparative efficacy of different vaccine platforms, particularly in the context of tumor burden (TB), remains insufficiently studied. In this research, we evaluated the safety and therapeutic efficacy of synthetic long...
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| Main Authors: | Cao Minh Nguyen, Trung T. Vu, Minh Nguyen Nguyen, Thao-Suong Tran-Nguyen, Chi Thien Huynh, Quang Thanh Ha, Hoai-Nghia Nguyen, Le Son Tran |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-03-01
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| Series: | Cancer Immunology, Immunotherapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00262-025-03992-7 |
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