ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION
Abstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluate...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/364 |
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| author | E. S. Ageeva V. M. Iptyshev O. V. Stygasheva N. V. Ryasantseva |
| author_facet | E. S. Ageeva V. M. Iptyshev O. V. Stygasheva N. V. Ryasantseva |
| author_sort | E. S. Ageeva |
| collection | DOAJ |
| description | Abstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluated. Some alterations of immunological indexes were revealed in patients infected with Helicobacter pylori, as compared to healthy donors and migrants. The changes were characterized by a more intense apoptotic death of lymphocytes in the patients, when compared with numbers of apoptotic cells in control group. Probable role of apoptotic events in regulation of local and system immunity in Helicobacter pylori infection is discussed. |
| format | Article |
| id | doaj-art-4e1ecf47f7d2401e8da3ffcf59f96645 |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-4e1ecf47f7d2401e8da3ffcf59f966452025-08-20T03:37:46ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0114324925410.15789/1563-0625-2012-3-249-254361ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTIONE. S. Ageeva0V. M. Iptyshev1O. V. Stygasheva2N. V. Ryasantseva3ГОУ ВПО «Хакасский государственный университет им. Н.Ф. Катанова», г. АбаканГУЗ «Хакасская Республиканская больница им. Г.Я. Ремишевской», г. АбаканГОУ ВПО «Хакасский государственный университет им. Н.Ф. Катанова», г. АбаканГОУ ВПО «Сибирский государственный медицинский университет» Минздравсоцразвития России, г. ТомскAbstract. Immunophenotype profile of lymphocytes (CD3+, CD4+ and CD8+) from peripheral blood in gastric ulcer associated with Helicobacter pylori, chronic gastritis and stomach cancer has been studied in Khakassian aboriginals and migrants. Apoptosis of peripheral blood lymphocytes was also evaluated. Some alterations of immunological indexes were revealed in patients infected with Helicobacter pylori, as compared to healthy donors and migrants. The changes were characterized by a more intense apoptotic death of lymphocytes in the patients, when compared with numbers of apoptotic cells in control group. Probable role of apoptotic events in regulation of local and system immunity in Helicobacter pylori infection is discussed.https://www.mimmun.ru/mimmun/article/view/364helicobacter pyloristomach cancergastric ulcerlymphocytescd markersapoptosis |
| spellingShingle | E. S. Ageeva V. M. Iptyshev O. V. Stygasheva N. V. Ryasantseva ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION Медицинская иммунология helicobacter pylori stomach cancer gastric ulcer lymphocytes cd markers apoptosis |
| title | ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION |
| title_full | ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION |
| title_fullStr | ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION |
| title_full_unstemmed | ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION |
| title_short | ETHNIC AND POPULATION-SPECIFIC FEATURES OF SOME IMMUNOLOGICAL PARAMETERS IN CHRONIC HELICOBACTER PYLORI INFECTION |
| title_sort | ethnic and population specific features of some immunological parameters in chronic helicobacter pylori infection |
| topic | helicobacter pylori stomach cancer gastric ulcer lymphocytes cd markers apoptosis |
| url | https://www.mimmun.ru/mimmun/article/view/364 |
| work_keys_str_mv | AT esageeva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection AT vmiptyshev ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection AT ovstygasheva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection AT nvryasantseva ethnicandpopulationspecificfeaturesofsomeimmunologicalparametersinchronichelicobacterpyloriinfection |