Iron deficiency in pulmonary arterial hypertension: perspectives
In left heart failure, iron supplementation (IS) is a first‐line treatment option, regardless of anemia. Pulmonary arterial hypertension (PAH), a rare disease leading to right heart failure, is also associated with iron deficiency. While it is a much debated topic, recent evidence demonstrate that r...
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| Format: | Article |
| Language: | English |
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Wiley
2021-07-01
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| Series: | Pulmonary Circulation |
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| Online Access: | https://doi.org/10.1177/20458940211021301 |
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| _version_ | 1850193441556791296 |
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| author | Marceau Quatredeniers David Montani Alain Cohen‐Solal Frédéric Perros |
| author_facet | Marceau Quatredeniers David Montani Alain Cohen‐Solal Frédéric Perros |
| author_sort | Marceau Quatredeniers |
| collection | DOAJ |
| description | In left heart failure, iron supplementation (IS) is a first‐line treatment option, regardless of anemia. Pulmonary arterial hypertension (PAH), a rare disease leading to right heart failure, is also associated with iron deficiency. While it is a much debated topic, recent evidence demonstrate that restoration of iron stores results in improved right ventricular function and exercise tolerance. Hence, IS may also be considered as an option in the treatment of PAH. |
| format | Article |
| id | doaj-art-4e1cf267eb494a41acf6b3718da17798 |
| institution | OA Journals |
| issn | 2045-8940 |
| language | English |
| publishDate | 2021-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Circulation |
| spelling | doaj-art-4e1cf267eb494a41acf6b3718da177982025-08-20T02:14:16ZengWileyPulmonary Circulation2045-89402021-07-011131410.1177/20458940211021301Iron deficiency in pulmonary arterial hypertension: perspectivesMarceau Quatredeniers0David Montani1Alain Cohen‐Solal2Frédéric Perros3Université Paris–SaclayAP‐HP, INSERM UMR_S 999Service de Pneumologie et Soins Intensifs RespiratoiresHôpital de BicêtreLe Kremlin BicêtreFranceUniversité Paris–SaclayAP‐HP, INSERM UMR_S 999Service de Pneumologie et Soins Intensifs RespiratoiresHôpital de BicêtreLe Kremlin BicêtreFranceDepartment of CardiologyLariboisière HospitalUniversity of ParisINSERM UMR_S 942ParisFranceUniversité Paris–SaclayAP‐HP, INSERM UMR_S 999Service de Pneumologie et Soins Intensifs RespiratoiresHôpital de BicêtreLe Kremlin BicêtreFranceIn left heart failure, iron supplementation (IS) is a first‐line treatment option, regardless of anemia. Pulmonary arterial hypertension (PAH), a rare disease leading to right heart failure, is also associated with iron deficiency. While it is a much debated topic, recent evidence demonstrate that restoration of iron stores results in improved right ventricular function and exercise tolerance. Hence, IS may also be considered as an option in the treatment of PAH.https://doi.org/10.1177/20458940211021301right heart failurehepcidiniron supplementation |
| spellingShingle | Marceau Quatredeniers David Montani Alain Cohen‐Solal Frédéric Perros Iron deficiency in pulmonary arterial hypertension: perspectives Pulmonary Circulation right heart failure hepcidin iron supplementation |
| title | Iron deficiency in pulmonary arterial hypertension: perspectives |
| title_full | Iron deficiency in pulmonary arterial hypertension: perspectives |
| title_fullStr | Iron deficiency in pulmonary arterial hypertension: perspectives |
| title_full_unstemmed | Iron deficiency in pulmonary arterial hypertension: perspectives |
| title_short | Iron deficiency in pulmonary arterial hypertension: perspectives |
| title_sort | iron deficiency in pulmonary arterial hypertension perspectives |
| topic | right heart failure hepcidin iron supplementation |
| url | https://doi.org/10.1177/20458940211021301 |
| work_keys_str_mv | AT marceauquatredeniers irondeficiencyinpulmonaryarterialhypertensionperspectives AT davidmontani irondeficiencyinpulmonaryarterialhypertensionperspectives AT alaincohensolal irondeficiencyinpulmonaryarterialhypertensionperspectives AT fredericperros irondeficiencyinpulmonaryarterialhypertensionperspectives |