Aniline Derivatives Containing 1-Substituted 1,2,3-Triazole System as Potential Drug Candidates: Pharmacokinetic Profile Prediction, Lipophilicity Analysis Using Experimental and In Silico Studies

Aniline Derivatives Containing 1-Substituted 1,2,3-Triazole System as Potential Drug Candidates: Pharmacokinetic Profile Prediction, Lipophilicity Analysis Using Experimental and In Silico Studies

<b>Background</b>: The triazole ring is an attractive structural unit in medicinal chemistry, and chemical compounds containing this type of system in their structure exhibit a wide spectrum of biological activity. They are used in the development of new pharmaceuticals. One of the basic...

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Bibliographic Details
Main Authors: Elwira Chrobak, Katarzyna Bober-Majnusz, Mirosław Wyszomirski, Andrzej Zięba
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
triazole
lipophilicity
RP-TLC
drug-likeness
Online Access:https://www.mdpi.com/1424-8247/17/11/1476
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