CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY
Objective: to analyze the incidence of giant-cell arteritis (GCA) in the Khabarovsk Territory.Subjects and methods. Ten (11.6%) cases of GCA identified during a 20-year prospective follow-up and treatment of 89 patients with polymyalgia rheumatica (PR) and GCA were analyzed. The rate of some criteri...
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IMA PRESS LLC
2011-06-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1291 |
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| author | E. N. Otteva T. Yu. Kocherova |
| author_facet | E. N. Otteva T. Yu. Kocherova |
| author_sort | E. N. Otteva |
| collection | DOAJ |
| description | Objective: to analyze the incidence of giant-cell arteritis (GCA) in the Khabarovsk Territory.Subjects and methods. Ten (11.6%) cases of GCA identified during a 20-year prospective follow-up and treatment of 89 patients with polymyalgia rheumatica (PR) and GCA were analyzed. The rate of some criteria for the diagnosis of GCA was estimated; its onset and paraclinical data were described. The study enrolled women aged 67.3±2.1 years (range 59 to 76 years). Results and discussion. GCA concurrent with PR was observed in 70% of cases. In addition to temporal arteritis, there was a clinical picture of involvements of the parietal (50%), ocular (30%), occipital (30%), and coronary (10%) arteries. Scalp involvement with necrosis in the parietal area was found in one case. The diagnosis was established after an average of 71±1.6 months. All had elevated ESR, up to 110.2±3.1 on average after Westergren. Seven patients were treated with prednisolone 1.0 mg/kg body weight; due to contraindications, 6 patients had 0.5 mg/kg in combination with pulse therapy with cyclophosphanum 1000 mg intravenously, dropwise once monthly. One female patient died from stroke 4 months later. The late period was marked by the development of osteoporosis with fractures in 2 cases, diabetes mellitus and hypertension in 2, and cancer of the cervix uteri (successfully cured) in one case. Vision loss was seen in one patient whose diagnosis was made 1.5 years later. |
| format | Article |
| id | doaj-art-4e10545623c443c3bea61353d5a2c9d6 |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2011-06-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-4e10545623c443c3bea61353d5a2c9d62025-08-20T03:38:12ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922011-06-01495384510.14412/1995-4484-2011-14591231CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORYE. N. Otteva0T. Yu. Kocherovaelvott@mail.ruObjective: to analyze the incidence of giant-cell arteritis (GCA) in the Khabarovsk Territory.Subjects and methods. Ten (11.6%) cases of GCA identified during a 20-year prospective follow-up and treatment of 89 patients with polymyalgia rheumatica (PR) and GCA were analyzed. The rate of some criteria for the diagnosis of GCA was estimated; its onset and paraclinical data were described. The study enrolled women aged 67.3±2.1 years (range 59 to 76 years). Results and discussion. GCA concurrent with PR was observed in 70% of cases. In addition to temporal arteritis, there was a clinical picture of involvements of the parietal (50%), ocular (30%), occipital (30%), and coronary (10%) arteries. Scalp involvement with necrosis in the parietal area was found in one case. The diagnosis was established after an average of 71±1.6 months. All had elevated ESR, up to 110.2±3.1 on average after Westergren. Seven patients were treated with prednisolone 1.0 mg/kg body weight; due to contraindications, 6 patients had 0.5 mg/kg in combination with pulse therapy with cyclophosphanum 1000 mg intravenously, dropwise once monthly. One female patient died from stroke 4 months later. The late period was marked by the development of osteoporosis with fractures in 2 cases, diabetes mellitus and hypertension in 2, and cancer of the cervix uteri (successfully cured) in one case. Vision loss was seen in one patient whose diagnosis was made 1.5 years later.https://rsp.mediar-press.net/rsp/article/view/1291giant cell arteritispolymyalgia rheumatica,diagnostic criteriaclucocorticoid therapy |
| spellingShingle | E. N. Otteva T. Yu. Kocherova CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY Научно-практическая ревматология giant cell arteritis polymyalgia rheumatica, diagnostic criteria clucocorticoid therapy |
| title | CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY |
| title_full | CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY |
| title_fullStr | CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY |
| title_full_unstemmed | CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY |
| title_short | CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY |
| title_sort | current view of horton s disease analysis of its cases in the khabarovsk territory |
| topic | giant cell arteritis polymyalgia rheumatica, diagnostic criteria clucocorticoid therapy |
| url | https://rsp.mediar-press.net/rsp/article/view/1291 |
| work_keys_str_mv | AT enotteva currentviewofhortonsdiseaseanalysisofitscasesinthekhabarovskterritory AT tyukocherova currentviewofhortonsdiseaseanalysisofitscasesinthekhabarovskterritory |