Computed Tomographic Hepatic Volumetry in Dogs with Congenital Portosystemic Shunts
CTHV is a non-invasive and accurate method for assessing liver volume in dogs. CTHV has not been studied in each type of extrahepatic PSS in dogs. This study aimed to use CTHV to compare liver volumes in dogs with different types of PSSs that had been confirmed by computed tomography angiography. Do...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-08-01
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| Series: | Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-7381/11/9/390 |
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| Summary: | CTHV is a non-invasive and accurate method for assessing liver volume in dogs. CTHV has not been studied in each type of extrahepatic PSS in dogs. This study aimed to use CTHV to compare liver volumes in dogs with different types of PSSs that had been confirmed by computed tomography angiography. Dogs with PSSs were retrospectively included and categorized into IH, EHPC, EHPA, or EHPP shunt groups. Manual CTHV was performed, and the normalized liver volume (nLV) and the difference in nLV from the estimated liver volume calculated based on body weight (LV%diff) was calculated. The study included 57 dogs: 20 IH, 21 EHPC, 9 EHPA, and 7 EHPP. The median nLV (cm<sup>3</sup>/kg) and LV%diff (%) for each group were as follows: IH 17.3 (−40.4%); EHPC 16.9 (−60.3%); EHPA 15.1 (−56.7%); and EHPP 17.2 (−59.2%), respectively. There were no significant differences in nLV among the PSS types. However, LV%diff was significantly more pronounced in the EHPC and EHPA groups compared with the IH group. Additionally, smaller dogs exhibited more severe microhepatia, with a significant positive correlation between LV%diff and body weight (<i>p</i> < 0.01). These findings suggest that microhepatia severity varies by shunt type and is more severe in smaller dogs, highlighting the need for further research to understand the underlying mechanisms. |
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| ISSN: | 2306-7381 |