Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects
Abstract In the current work, CeO2‐NPs were produced via a green chemistry process via Linum usitatissimum seeds extract as the stabilizing agent. The CeO2‐NPs were characterized by the results of analytical techniques such as TGA/DTA, FTIR, UV–vis, XPS, XRD, and FESEM/PSA/EDX. The outcomes of the X...
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| Format: | Article |
| Language: | English |
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Wiley
2024-11-01
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| Series: | Micro & Nano Letters |
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| Online Access: | https://doi.org/10.1049/mna2.70003 |
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| author | Zahra Foroutan Zahra Sabouri Amir Reza Afshari Asma Mostafapour Bahareh Farasati Far Mohammad Jalili‐Nik Majid Darroudi |
| author_facet | Zahra Foroutan Zahra Sabouri Amir Reza Afshari Asma Mostafapour Bahareh Farasati Far Mohammad Jalili‐Nik Majid Darroudi |
| author_sort | Zahra Foroutan |
| collection | DOAJ |
| description | Abstract In the current work, CeO2‐NPs were produced via a green chemistry process via Linum usitatissimum seeds extract as the stabilizing agent. The CeO2‐NPs were characterized by the results of analytical techniques such as TGA/DTA, FTIR, UV–vis, XPS, XRD, and FESEM/PSA/EDX. The outcomes of the XRD pattern affirmed the crystalline structure of this product with the suggested size of about 20 nm, while the FESEM/PSA pictures presented spherical morphology. Additionally, the XPS analysis of CeO2‐NPs affirmed the presence of a Ce+3 oxidation state in the sample, as well as Ce+4 as the major valence of cerium oxide. The results of the MTT test on Huh‐7 cancer cells and HFF normal cells displayed the lack of any significant cytotoxicity even at concentrations up to 1000 µg/mL. Therefore, the obtained synthesized CeO2‐NPs through this green method could be suggested as a prospective agent for medical applications due to its non‐toxic effects. |
| format | Article |
| id | doaj-art-4de8a2ca2b8846baac81bdeebc975bff |
| institution | OA Journals |
| issn | 1750-0443 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Micro & Nano Letters |
| spelling | doaj-art-4de8a2ca2b8846baac81bdeebc975bff2025-08-20T02:23:34ZengWileyMicro & Nano Letters1750-04432024-11-01196n/an/a10.1049/mna2.70003Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effectsZahra Foroutan0Zahra Sabouri1Amir Reza Afshari2Asma Mostafapour3Bahareh Farasati Far4Mohammad Jalili‐Nik5Majid Darroudi6Department of Medical Biotechnology & Nanotechnology, Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Medical Biotechnology & Nanotechnology, Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Physiology and Pharmacology, Faculty of Medicine North Khorasan University of Medical Sciences Bojnurd IranDepartment of Medical Biotechnology & Nanotechnology, Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Chemistry Iran University of Science and Technology Tehran IranDepartment of Medical Biochemistry, Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Medical Biotechnology & Nanotechnology, Faculty of Medicine Mashhad University of Medical Sciences Mashhad IranAbstract In the current work, CeO2‐NPs were produced via a green chemistry process via Linum usitatissimum seeds extract as the stabilizing agent. The CeO2‐NPs were characterized by the results of analytical techniques such as TGA/DTA, FTIR, UV–vis, XPS, XRD, and FESEM/PSA/EDX. The outcomes of the XRD pattern affirmed the crystalline structure of this product with the suggested size of about 20 nm, while the FESEM/PSA pictures presented spherical morphology. Additionally, the XPS analysis of CeO2‐NPs affirmed the presence of a Ce+3 oxidation state in the sample, as well as Ce+4 as the major valence of cerium oxide. The results of the MTT test on Huh‐7 cancer cells and HFF normal cells displayed the lack of any significant cytotoxicity even at concentrations up to 1000 µg/mL. Therefore, the obtained synthesized CeO2‐NPs through this green method could be suggested as a prospective agent for medical applications due to its non‐toxic effects.https://doi.org/10.1049/mna2.70003cancerceriumnanoparticles |
| spellingShingle | Zahra Foroutan Zahra Sabouri Amir Reza Afshari Asma Mostafapour Bahareh Farasati Far Mohammad Jalili‐Nik Majid Darroudi Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects Micro & Nano Letters cancer cerium nanoparticles |
| title | Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects |
| title_full | Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects |
| title_fullStr | Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects |
| title_full_unstemmed | Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects |
| title_short | Green synthesis of cerium oxide nanoparticles via Linum usitatissimum seeds extract and assessment of its biological effects |
| title_sort | green synthesis of cerium oxide nanoparticles via linum usitatissimum seeds extract and assessment of its biological effects |
| topic | cancer cerium nanoparticles |
| url | https://doi.org/10.1049/mna2.70003 |
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