Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase

Antibiotics, although developed for curing bacterial infections, contaminate the environment, and their long-term unintentional exposure has detrimental effects on the environment, human health, and other organisms, leading to antibacterial resistance, genotoxicity, birth deformities, inhibition of...

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Main Authors: Nidhi Sikri, Sandeep Kumar, Bunushree Behera, Jyotsana Mehta
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Nanotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2025.1578620/full
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author Nidhi Sikri
Sandeep Kumar
Bunushree Behera
Jyotsana Mehta
author_facet Nidhi Sikri
Sandeep Kumar
Bunushree Behera
Jyotsana Mehta
author_sort Nidhi Sikri
collection DOAJ
description Antibiotics, although developed for curing bacterial infections, contaminate the environment, and their long-term unintentional exposure has detrimental effects on the environment, human health, and other organisms, leading to antibacterial resistance, genotoxicity, birth deformities, inhibition of cell proliferation, and reduction of photosynthetic activity. Therefore, there is a compelling need to remove antibiotic contaminants from water reservoirs, and nano-platforms are emerging as attractive platforms for environmental remediation. In this regard, a composite of graphene oxide (GO) with ZnAlNi layered double hydroxide (LDH) has been explored for highly efficient adsorptive removal of priority antibiotic, ciprofloxacin (CIP). The composite containing ZnAlNi-LDH with specific removal capability towards CIP and GO displaying high surface area for adsorption has been synthesized using the co-precipitation method followed by hydrothermal aging. The formed adsorbent has been structurally characterized using several analytical instrumentation techniques demonstrating its potential for antibiotic adsorption. The adsorption of CIP onto GO-ZnAlNi LDH has been studied by varying several parameters including contact time, pH, adsorbent, and adsorbate concentration. The composite demonstrated more than 80% removal of CIP at 1 mg/L initial concentration from the aqueous solution in 1 h with 10 mg/L adsorbent at pH 7. The kinetics of adsorption fits well with pseudo-first-order model, Elovich model and equilibrium adsorption capacity of 106.97 mg/g was obtained. The composite platform also exhibited high stability, regeneration, and reusability up to five cycles.
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spelling doaj-art-4de3e51b172e4e669a526a695851268f2025-08-20T02:17:29ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132025-04-01710.3389/fnano.2025.15786201578620Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phaseNidhi Sikri0Sandeep Kumar1Bunushree Behera2Jyotsana Mehta3Department of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, Punjab, IndiaDepartment of Physics, Punjab Engineering College (Deemed to be University), Chandigarh, IndiaDepartment of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, Punjab, IndiaDepartment of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, Punjab, IndiaAntibiotics, although developed for curing bacterial infections, contaminate the environment, and their long-term unintentional exposure has detrimental effects on the environment, human health, and other organisms, leading to antibacterial resistance, genotoxicity, birth deformities, inhibition of cell proliferation, and reduction of photosynthetic activity. Therefore, there is a compelling need to remove antibiotic contaminants from water reservoirs, and nano-platforms are emerging as attractive platforms for environmental remediation. In this regard, a composite of graphene oxide (GO) with ZnAlNi layered double hydroxide (LDH) has been explored for highly efficient adsorptive removal of priority antibiotic, ciprofloxacin (CIP). The composite containing ZnAlNi-LDH with specific removal capability towards CIP and GO displaying high surface area for adsorption has been synthesized using the co-precipitation method followed by hydrothermal aging. The formed adsorbent has been structurally characterized using several analytical instrumentation techniques demonstrating its potential for antibiotic adsorption. The adsorption of CIP onto GO-ZnAlNi LDH has been studied by varying several parameters including contact time, pH, adsorbent, and adsorbate concentration. The composite demonstrated more than 80% removal of CIP at 1 mg/L initial concentration from the aqueous solution in 1 h with 10 mg/L adsorbent at pH 7. The kinetics of adsorption fits well with pseudo-first-order model, Elovich model and equilibrium adsorption capacity of 106.97 mg/g was obtained. The composite platform also exhibited high stability, regeneration, and reusability up to five cycles.https://www.frontiersin.org/articles/10.3389/fnano.2025.1578620/fullantibioticadsorptionciprofloxacingraphene oxidelayered double hydroxides
spellingShingle Nidhi Sikri
Sandeep Kumar
Bunushree Behera
Jyotsana Mehta
Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
Frontiers in Nanotechnology
antibiotic
adsorption
ciprofloxacin
graphene oxide
layered double hydroxides
title Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
title_full Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
title_fullStr Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
title_full_unstemmed Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
title_short Graphene oxide/layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
title_sort graphene oxide layered double hydroxide composite as highly efficient and recyclable adsorbent for removal of ciprofloxacin from aqueous phase
topic antibiotic
adsorption
ciprofloxacin
graphene oxide
layered double hydroxides
url https://www.frontiersin.org/articles/10.3389/fnano.2025.1578620/full
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AT sandeepkumar grapheneoxidelayereddoublehydroxidecompositeashighlyefficientandrecyclableadsorbentforremovalofciprofloxacinfromaqueousphase
AT bunushreebehera grapheneoxidelayereddoublehydroxidecompositeashighlyefficientandrecyclableadsorbentforremovalofciprofloxacinfromaqueousphase
AT jyotsanamehta grapheneoxidelayereddoublehydroxidecompositeashighlyefficientandrecyclableadsorbentforremovalofciprofloxacinfromaqueousphase