Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events
ABSTRACT In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all‐cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function du...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | The Journal of Clinical Hypertension |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jch.14934 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832576403198967808 |
|---|---|
| author | Zhenliang Fan Rujia Ye Qiaorui Yang Mengfan Yang Riping Yin Dongxue Zhao Junfen Fan Hongzhen Ma Yiwei Shen Hong Xia Wenze Jiang Keda Lu |
| author_facet | Zhenliang Fan Rujia Ye Qiaorui Yang Mengfan Yang Riping Yin Dongxue Zhao Junfen Fan Hongzhen Ma Yiwei Shen Hong Xia Wenze Jiang Keda Lu |
| author_sort | Zhenliang Fan |
| collection | DOAJ |
| description | ABSTRACT In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all‐cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function during the process of rapid clearance of volume overload, holds greater relevance to the prognosis of patients. In this study, a latent category trajectory model was used to identify the patterns of intradialytic BPV and analyze the association between intradialytic BPV and the cardio‐cerebrovascular events and other clinical outcomes. We found the variation of intradialytic systolic blood pressure (SBP) was associated with the risk of cardio‐cerebrovascular events in hemodialysis patients. Patients in “SBP Class 4” and “SBP Class 3” subgroups were associated with the occurrence of cardio‐cerebrovascular events and the number of cardio‐cerebrovascular event hospitalizations during the follow‐up period. This indicates that the variation pattern of intradialytic SBP results from the comprehensive action of various BP regulatory mechanisms in the body, which can reflect the level of cardiovascular regulatory function in hemodialysis patients and serve as a predictor of recent adverse cardio‐cerebrovascular events. |
| format | Article |
| id | doaj-art-4dd757c0153f473ba4132d7777d7cf69 |
| institution | Kabale University |
| issn | 1524-6175 1751-7176 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj-art-4dd757c0153f473ba4132d7777d7cf692025-01-31T05:38:36ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762025-01-01271n/an/a10.1111/jch.14934Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular EventsZhenliang Fan0Rujia Ye1Qiaorui Yang2Mengfan Yang3Riping Yin4Dongxue Zhao5Junfen Fan6Hongzhen Ma7Yiwei Shen8Hong Xia9Wenze Jiang10Keda Lu11Nephrology Department The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine) Hangzhou ChinaNephrology Department Yueqing Hospital of Traditional Chinese Medicine Yueqing ChinaDepartment of Gynecology Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai ChinaGraduate School Chengdu Chinese Medical University Chengdu ChinaNephrology and Endocrinology Department Pinghu Hospital of Traditional Chinese Medicine Pinghu ChinaHealth Institute, Harbin Institute of Physical Education Harbin ChinaNephrology Department The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine) Hangzhou ChinaNephrology Department The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine) Hangzhou ChinaOrthopedics Department Ningbo Hospital of Traditional Chinese Medicine (Ningbo Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine) Ningbo ChinaNephrology Department The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine) Hangzhou ChinaDepartment of Nephrology The Third Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou ChinaDepartment of Nephrology The Third Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou ChinaABSTRACT In hemodialysis patients, blood pressure variability (BPV) is associated with cardiovascular events and all‐cause mortality. However, previous research has predominantly concentrated on the predialysis BPV. In contrast, intradialytic BPV, reflecting the cardiovascular regulatory function during the process of rapid clearance of volume overload, holds greater relevance to the prognosis of patients. In this study, a latent category trajectory model was used to identify the patterns of intradialytic BPV and analyze the association between intradialytic BPV and the cardio‐cerebrovascular events and other clinical outcomes. We found the variation of intradialytic systolic blood pressure (SBP) was associated with the risk of cardio‐cerebrovascular events in hemodialysis patients. Patients in “SBP Class 4” and “SBP Class 3” subgroups were associated with the occurrence of cardio‐cerebrovascular events and the number of cardio‐cerebrovascular event hospitalizations during the follow‐up period. This indicates that the variation pattern of intradialytic SBP results from the comprehensive action of various BP regulatory mechanisms in the body, which can reflect the level of cardiovascular regulatory function in hemodialysis patients and serve as a predictor of recent adverse cardio‐cerebrovascular events.https://doi.org/10.1111/jch.14934blood pressure variabilitycardio‐cerebrovascular eventshemodialysislatent category trajectory model |
| spellingShingle | Zhenliang Fan Rujia Ye Qiaorui Yang Mengfan Yang Riping Yin Dongxue Zhao Junfen Fan Hongzhen Ma Yiwei Shen Hong Xia Wenze Jiang Keda Lu Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events The Journal of Clinical Hypertension blood pressure variability cardio‐cerebrovascular events hemodialysis latent category trajectory model |
| title | Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events |
| title_full | Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events |
| title_fullStr | Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events |
| title_full_unstemmed | Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events |
| title_short | Association Between Blood Pressure Variation During Dialysis and Cardio‐Cerebrovascular Events |
| title_sort | association between blood pressure variation during dialysis and cardio cerebrovascular events |
| topic | blood pressure variability cardio‐cerebrovascular events hemodialysis latent category trajectory model |
| url | https://doi.org/10.1111/jch.14934 |
| work_keys_str_mv | AT zhenliangfan associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT rujiaye associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT qiaoruiyang associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT mengfanyang associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT ripingyin associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT dongxuezhao associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT junfenfan associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT hongzhenma associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT yiweishen associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT hongxia associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT wenzejiang associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents AT kedalu associationbetweenbloodpressurevariationduringdialysisandcardiocerebrovascularevents |