Is there any relationship between initial hematological parameters and severity of scorpion envenomation?
Background and Objectives. Most cases of severe scorpion envenomation occur in children and are associated with significant morbidity and mortality. Excessive systemic inflammatory response, which leads to multiple organ involvement, is an emerging challenge during severe envenomation. The ai...
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Hacettepe University Institute of Child Health
2020-06-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/459 |
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| author | Özden Özgür Horoz Dinçer Yıldızdaş Nagehan Aslan Sinem Sarı Gökay Faruk Ekinci Sevcan Erdem Zeliha Haytoğlu Yaşar Sertdemir Hayri Levent Yılmaz |
| author_facet | Özden Özgür Horoz Dinçer Yıldızdaş Nagehan Aslan Sinem Sarı Gökay Faruk Ekinci Sevcan Erdem Zeliha Haytoğlu Yaşar Sertdemir Hayri Levent Yılmaz |
| author_sort | Özden Özgür Horoz |
| collection | DOAJ |
| description |
Background and Objectives. Most cases of severe scorpion envenomation occur in children and are associated with significant morbidity and mortality. Excessive systemic inflammatory response, which leads to multiple organ involvement, is an emerging challenge during severe envenomation. The aim of this study was to investigate if there was any relationship between initial hematological parameters and severe envenomation in pediatric patients presenting with scorpion envenomation.
Method. This study was performed retrospectively, at the pediatric emergency unit and pediatric intensive care unit of the Çukurova University Medical School in Turkey. Two hundred and fifty-seven cases with scorpion envenomation, and a control group consisting of one hundred and fifteen healthy children were included in the study.
Results. White blood cell, neutrophil, lymphocyte, platelet, neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR) and PDW values of patients were higher than the controls (p < 0.05). Mean NLR was 3.8 ± 4.7 in patients. Patients were analyzed with the help of the decision tree model, and it was seen that in patients who had applied to hospital in less than an hour after the scorpion sting, 87.5% of the patients whose NLR value was between the 0.519-1.969 interval (below 2.1 which we found as the cut-off value) did not need to be hospitalized in the intensive care unit, 54.1% of the patients whose NLR value was higher than 1.969 needed to be hospitalized at the intensive care unit.
Conclusions. Severe envenomation is associated with mortality and morbidity in children. Our findings showed that NLR seems to be a useful tool in predicting severe envenomation.
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| format | Article |
| id | doaj-art-4dd70c1153c846bfaae26e90493fe02f |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-4dd70c1153c846bfaae26e90493fe02f2025-08-20T03:00:53ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212020-06-0162310.24953/turkjped.2020.03.006Is there any relationship between initial hematological parameters and severity of scorpion envenomation?Özden Özgür Horoz0Dinçer Yıldızdaş1Nagehan Aslan2Sinem Sarı Gökay3Faruk Ekinci4Sevcan Erdem5Zeliha Haytoğlu6Yaşar Sertdemir7Hayri Levent Yılmaz8Divisions of Pediatric Intensive Care Unit, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Intensive Care Unit, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Intensive Care Unit, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Emergency, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Intensive Care Unit, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Cardiology,Çukurova University Faculty of Medicine, Adana, Turkey.Department of Pediatric, Çukurova University Faculty of Medicine, Adana, Turkey.Department of Biostatistics, Çukurova University Faculty of Medicine, Adana, Turkey.Divisions of Pediatric Emergency, Çukurova University Faculty of Medicine, Adana, Turkey. Background and Objectives. Most cases of severe scorpion envenomation occur in children and are associated with significant morbidity and mortality. Excessive systemic inflammatory response, which leads to multiple organ involvement, is an emerging challenge during severe envenomation. The aim of this study was to investigate if there was any relationship between initial hematological parameters and severe envenomation in pediatric patients presenting with scorpion envenomation. Method. This study was performed retrospectively, at the pediatric emergency unit and pediatric intensive care unit of the Çukurova University Medical School in Turkey. Two hundred and fifty-seven cases with scorpion envenomation, and a control group consisting of one hundred and fifteen healthy children were included in the study. Results. White blood cell, neutrophil, lymphocyte, platelet, neutrophil/lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR) and PDW values of patients were higher than the controls (p < 0.05). Mean NLR was 3.8 ± 4.7 in patients. Patients were analyzed with the help of the decision tree model, and it was seen that in patients who had applied to hospital in less than an hour after the scorpion sting, 87.5% of the patients whose NLR value was between the 0.519-1.969 interval (below 2.1 which we found as the cut-off value) did not need to be hospitalized in the intensive care unit, 54.1% of the patients whose NLR value was higher than 1.969 needed to be hospitalized at the intensive care unit. Conclusions. Severe envenomation is associated with mortality and morbidity in children. Our findings showed that NLR seems to be a useful tool in predicting severe envenomation. https://turkjpediatr.org/article/view/459childrenneutrophil/lymphocyte ratioscorpionsevere envenomation |
| spellingShingle | Özden Özgür Horoz Dinçer Yıldızdaş Nagehan Aslan Sinem Sarı Gökay Faruk Ekinci Sevcan Erdem Zeliha Haytoğlu Yaşar Sertdemir Hayri Levent Yılmaz Is there any relationship between initial hematological parameters and severity of scorpion envenomation? The Turkish Journal of Pediatrics children neutrophil/lymphocyte ratio scorpion severe envenomation |
| title | Is there any relationship between initial hematological parameters and severity of scorpion envenomation? |
| title_full | Is there any relationship between initial hematological parameters and severity of scorpion envenomation? |
| title_fullStr | Is there any relationship between initial hematological parameters and severity of scorpion envenomation? |
| title_full_unstemmed | Is there any relationship between initial hematological parameters and severity of scorpion envenomation? |
| title_short | Is there any relationship between initial hematological parameters and severity of scorpion envenomation? |
| title_sort | is there any relationship between initial hematological parameters and severity of scorpion envenomation |
| topic | children neutrophil/lymphocyte ratio scorpion severe envenomation |
| url | https://turkjpediatr.org/article/view/459 |
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