Template-based modeling of insect odorant receptors outperforms AlphaFold3 for ligand binding predictions
Abstract Insects rely on odorant receptors (ORs) to detect and respond to volatile environmental cues, so the ORs are attracting increasing interest as potential targets for pest control. However, experimental analysis of their structures and functions faces significant challenges. Computational met...
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| Main Authors: | Amara Jabeen, John Graham Oakeshott, Siu Fai Lee, Shoba Ranganathan, Phillip W. Taylor |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-80094-x |
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