Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19
Introduction: This study aims to research the effects of hematological and inflammatory parameters on the prognosis of COVID-19 disease and hospitalization duration. Methodology: One hundred and eighty-six patients with COVID-19 and a control group consisting of 187 healthy individuals were incl...
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The Journal of Infection in Developing Countries
2022-10-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/14341 |
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| author | Çiğdem Mermutluoğlu Recep Dursun Fesih Aktar Saim Dayan Mustafa Kemal Çelen Ali Kemal Kadiroğlu Erdal İnci Rengin Karagöz Mahir Kuyumcu Nida Özcan Recep Tekin |
| author_facet | Çiğdem Mermutluoğlu Recep Dursun Fesih Aktar Saim Dayan Mustafa Kemal Çelen Ali Kemal Kadiroğlu Erdal İnci Rengin Karagöz Mahir Kuyumcu Nida Özcan Recep Tekin |
| author_sort | Çiğdem Mermutluoğlu |
| collection | DOAJ |
| description |
Introduction: This study aims to research the effects of hematological and inflammatory parameters on the prognosis of COVID-19 disease and hospitalization duration.
Methodology: One hundred and eighty-six patients with COVID-19 and a control group consisting of 187 healthy individuals were included in the study. Hematological variables and inflammatory parameters of the patients were recorded on the first and the fifth days of hospitalization.
Results: White blood cell count, lymphocyte count, and platelet count were statistically lower, and mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) levels were higher in the patient group compared to the control group. It was observed that the neutrophil count and MPV level were lower, and the platelet count and ferritin level were statistically higher on the fifth day of follow-up compared to the admission day. In contrast, there was a significantly positive correlation between the duration of hospitalization and the fifth day D-dimer (r = 0.546, p < 0.001) and ferritin (r = 0.568, p < 0.001); in addition, there was a negative correlation between the duration of hospitalization and admission day lymphocyte count and the fifth-day lymphocyte count.
Conclusions: Increased levels of ferritin and D-dimer, and decreased count of lymphocytes are among the important factors affecting the duration of hospitalization for COVID-19 patients. Furthermore, we think that neutrophil count and MPV levels are low, and platelet count and ferritin levels are high during the disease. Therefore, these parameters can be used as prognostic indicators of the disease.
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| format | Article |
| id | doaj-art-4da561af014c4ec591d1431e71b21743 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-4da561af014c4ec591d1431e71b217432025-08-20T02:57:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802022-10-01161010.3855/jidc.14341Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19Çiğdem Mermutluoğlu0Recep Dursun1Fesih Aktar2Saim Dayan3Mustafa Kemal Çelen4Ali Kemal Kadiroğlu5Erdal İnci6Rengin Karagöz7Mahir Kuyumcu8Nida Özcan9Recep Tekin10Department of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Emergency Medicine, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Pediatric Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Internal Medicine, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Anesthesiology and Reanimation, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Microbiology, Dicle University Faculty of Medicine, Diyarbakir, TurkeyDepartment of Clinical Microbiology and Infectious Disease, Dicle University Faculty of Medicine, Diyarbakir, Turkey Introduction: This study aims to research the effects of hematological and inflammatory parameters on the prognosis of COVID-19 disease and hospitalization duration. Methodology: One hundred and eighty-six patients with COVID-19 and a control group consisting of 187 healthy individuals were included in the study. Hematological variables and inflammatory parameters of the patients were recorded on the first and the fifth days of hospitalization. Results: White blood cell count, lymphocyte count, and platelet count were statistically lower, and mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR) levels were higher in the patient group compared to the control group. It was observed that the neutrophil count and MPV level were lower, and the platelet count and ferritin level were statistically higher on the fifth day of follow-up compared to the admission day. In contrast, there was a significantly positive correlation between the duration of hospitalization and the fifth day D-dimer (r = 0.546, p < 0.001) and ferritin (r = 0.568, p < 0.001); in addition, there was a negative correlation between the duration of hospitalization and admission day lymphocyte count and the fifth-day lymphocyte count. Conclusions: Increased levels of ferritin and D-dimer, and decreased count of lymphocytes are among the important factors affecting the duration of hospitalization for COVID-19 patients. Furthermore, we think that neutrophil count and MPV levels are low, and platelet count and ferritin levels are high during the disease. Therefore, these parameters can be used as prognostic indicators of the disease. https://jidc.org/index.php/journal/article/view/14341COVID-19infectionmarkerspandemic |
| spellingShingle | Çiğdem Mermutluoğlu Recep Dursun Fesih Aktar Saim Dayan Mustafa Kemal Çelen Ali Kemal Kadiroğlu Erdal İnci Rengin Karagöz Mahir Kuyumcu Nida Özcan Recep Tekin Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 Journal of Infection in Developing Countries COVID-19 infection markers pandemic |
| title | Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 |
| title_full | Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 |
| title_fullStr | Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 |
| title_full_unstemmed | Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 |
| title_short | Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19 |
| title_sort | evaluation of inflammatory and hematological parameters in patients diagnosed with covid 19 |
| topic | COVID-19 infection markers pandemic |
| url | https://jidc.org/index.php/journal/article/view/14341 |
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