The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient

Pheochromocytomas are rare catecholamine producing neuroendocrine tumors. The incidence of these tumors is estimated to affect 0.8 per 100,000 person-years and is most common in the fourth to fifth decade of life with equal prevalence in men and women. We describe a case of an 84-year-old male who p...

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Main Authors: Christina N. DiMaria, Lorena I. Rasquin, Wikien A. Hung Pinto
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2019/5707968
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author Christina N. DiMaria
Lorena I. Rasquin
Wikien A. Hung Pinto
author_facet Christina N. DiMaria
Lorena I. Rasquin
Wikien A. Hung Pinto
author_sort Christina N. DiMaria
collection DOAJ
description Pheochromocytomas are rare catecholamine producing neuroendocrine tumors. The incidence of these tumors is estimated to affect 0.8 per 100,000 person-years and is most common in the fourth to fifth decade of life with equal prevalence in men and women. We describe a case of an 84-year-old male who presented with cycling episodes of severe hypertension and hypotension after an elective cardiac catheterization. Workup of the labile blood pressure revealed a large suprarenal mass and free serum metanephrines (MN) 104 nmol/L (reference range 0.0-0.49 nmol/L) and normetanephrines (NMN) of 24 nmol/L (reference range 0.0-0.89 nmol/L), confirming the diagnosis of a pheochromocytoma. The patient’s labile blood pressure was a challenge to manage medically and improved only after aggressive hydration and an alpha-adrenergic antagonist. Of note, this is the second eldest patient known to be published to date with a pheochromocytoma.
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spelling doaj-art-4da5278d3d47436b9f396ba27dccbd1b2025-02-03T01:21:59ZengWileyCase Reports in Endocrinology2090-65012090-651X2019-01-01201910.1155/2019/57079685707968The Highs and Lows of an Unknown Pheochromocytoma in an Elderly PatientChristina N. DiMaria0Lorena I. Rasquin1Wikien A. Hung Pinto2Department of Internal Medicine, Einstein Medical Center, Philadelphia, PA, 19141, USADepartment of Internal Medicine, Einstein Medical Center, Philadelphia, PA, 19141, USADepartment of Internal Medicine, Einstein Medical Center, Philadelphia, PA, 19141, USAPheochromocytomas are rare catecholamine producing neuroendocrine tumors. The incidence of these tumors is estimated to affect 0.8 per 100,000 person-years and is most common in the fourth to fifth decade of life with equal prevalence in men and women. We describe a case of an 84-year-old male who presented with cycling episodes of severe hypertension and hypotension after an elective cardiac catheterization. Workup of the labile blood pressure revealed a large suprarenal mass and free serum metanephrines (MN) 104 nmol/L (reference range 0.0-0.49 nmol/L) and normetanephrines (NMN) of 24 nmol/L (reference range 0.0-0.89 nmol/L), confirming the diagnosis of a pheochromocytoma. The patient’s labile blood pressure was a challenge to manage medically and improved only after aggressive hydration and an alpha-adrenergic antagonist. Of note, this is the second eldest patient known to be published to date with a pheochromocytoma.http://dx.doi.org/10.1155/2019/5707968
spellingShingle Christina N. DiMaria
Lorena I. Rasquin
Wikien A. Hung Pinto
The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
Case Reports in Endocrinology
title The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
title_full The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
title_fullStr The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
title_full_unstemmed The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
title_short The Highs and Lows of an Unknown Pheochromocytoma in an Elderly Patient
title_sort highs and lows of an unknown pheochromocytoma in an elderly patient
url http://dx.doi.org/10.1155/2019/5707968
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