THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION
The article presents the analysis of the clinical case of development of chronic mixed TBE infection (TBE and ixodes tick-borne borreliosis) on the background of antibacterial therapy in an unvaccinated patient. For etiological verification were used ELISA assay methods, immunochip with fluorescence...
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| Format: | Article |
| Language: | Russian |
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The Publishing House Medicine and Enlightenment
2017-10-01
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| Series: | Медицина в Кузбассе |
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| Online Access: | http://mednauki.ru/index.php/MK/article/view/162 |
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| author | Анатолий Васильевич Субботин Данил Андреевич Этенко Владимир Александрович Семенов Мария Сергеевна Щербинина Ванда Вацлавовна Погодина Надежда Михайловна Колясникова Сергей Валерьевич Мошнегуц Татьяна Евгеньевна Бондаренко |
| author_facet | Анатолий Васильевич Субботин Данил Андреевич Этенко Владимир Александрович Семенов Мария Сергеевна Щербинина Ванда Вацлавовна Погодина Надежда Михайловна Колясникова Сергей Валерьевич Мошнегуц Татьяна Евгеньевна Бондаренко |
| author_sort | Анатолий Васильевич Субботин |
| collection | DOAJ |
| description | The article presents the analysis of the clinical case of development of chronic mixed TBE infection (TBE and ixodes tick-borne borreliosis) on the background of antibacterial therapy in an unvaccinated patient. For etiological verification were used ELISA assay methods, immunochip with fluorescence detection. In the diagnostic process was conducted EMG, CT and MRI studies. The patient had lesion brain and spinal cord caused by TBE infectious process, with B. garinii and B. afzelii.
Conclusion. 1. The stable detection of TBE IgG antibodies at a high level indicates the absence of depression of humoral immunity in the application of the antibiotic Ceftriaxone. 2. A long term persistence of IgM antibodies in serum to Lyme disease, identification of the TBE antigen in serum and IgG antibodies in the cerebrospinal fluid of a patient, indicates incomplete elimination of the pathogen on the background of the therapy, causing the patient developed chronic mixed focal forms of TBE with latent form of ixodes tick-borne borreliosis. 3. Patient exhibits clinical symptoms of TBE (Epilepsy of Kozhevnikov). |
| format | Article |
| id | doaj-art-4da2f8ae14a94089a187d7420a103cdf |
| institution | Kabale University |
| issn | 1819-0901 |
| language | Russian |
| publishDate | 2017-10-01 |
| publisher | The Publishing House Medicine and Enlightenment |
| record_format | Article |
| series | Медицина в Кузбассе |
| spelling | doaj-art-4da2f8ae14a94089a187d7420a103cdf2025-08-20T03:58:23ZrusThe Publishing House Medicine and EnlightenmentМедицина в Кузбассе1819-09012017-10-01164101106148THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGIONАнатолий Васильевич Субботин0Данил Андреевич Этенко1Владимир Александрович Семенов2Мария Сергеевна Щербинина3Ванда Вацлавовна Погодина4Надежда Михайловна Колясникова5Сергей Валерьевич Мошнегуц6Татьяна Евгеньевна Бондаренко7ФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБОУ ВО КемГМУ Минздрава России, г. КемеровоФГБНУ «ФНЦИРИП им. М.П. Чумакова РАН», г. Москва,ФГБНУ «ФНЦИРИП им. М.П. Чумакова РАН», г. МоскваФГБНУ «ФНЦИРИП им. М.П. Чумакова РАН», г. МоскваГАУЗ КОКБ, г. КемеровоГБУЗ КО «КОКИБ», г. КемеровоThe article presents the analysis of the clinical case of development of chronic mixed TBE infection (TBE and ixodes tick-borne borreliosis) on the background of antibacterial therapy in an unvaccinated patient. For etiological verification were used ELISA assay methods, immunochip with fluorescence detection. In the diagnostic process was conducted EMG, CT and MRI studies. The patient had lesion brain and spinal cord caused by TBE infectious process, with B. garinii and B. afzelii. Conclusion. 1. The stable detection of TBE IgG antibodies at a high level indicates the absence of depression of humoral immunity in the application of the antibiotic Ceftriaxone. 2. A long term persistence of IgM antibodies in serum to Lyme disease, identification of the TBE antigen in serum and IgG antibodies in the cerebrospinal fluid of a patient, indicates incomplete elimination of the pathogen on the background of the therapy, causing the patient developed chronic mixed focal forms of TBE with latent form of ixodes tick-borne borreliosis. 3. Patient exhibits clinical symptoms of TBE (Epilepsy of Kozhevnikov).http://mednauki.ru/index.php/MK/article/view/162хроническая смешанная клещевая инфекцияиксодовый клещевой боррелиозклещевой энцефалитгуморальный иммунитетантибактериальная терапияиммуноглобулин человека нормальный |
| spellingShingle | Анатолий Васильевич Субботин Данил Андреевич Этенко Владимир Александрович Семенов Мария Сергеевна Щербинина Ванда Вацлавовна Погодина Надежда Михайловна Колясникова Сергей Валерьевич Мошнегуц Татьяна Евгеньевна Бондаренко THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION Медицина в Кузбассе хроническая смешанная клещевая инфекция иксодовый клещевой боррелиоз клещевой энцефалит гуморальный иммунитет антибактериальная терапия иммуноглобулин человека нормальный |
| title | THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION |
| title_full | THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION |
| title_fullStr | THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION |
| title_full_unstemmed | THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION |
| title_short | THE CASE OF MIXED TICK-BORNE INFECTIONS – TICK-BORNE ENCEPHALITIS AND LYME DISEASE (B. GARINII, B. AFZELII) IN THE KEMEROVO REGION |
| title_sort | case of mixed tick borne infections tick borne encephalitis and lyme disease b garinii b afzelii in the kemerovo region |
| topic | хроническая смешанная клещевая инфекция иксодовый клещевой боррелиоз клещевой энцефалит гуморальный иммунитет антибактериальная терапия иммуноглобулин человека нормальный |
| url | http://mednauki.ru/index.php/MK/article/view/162 |
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