Impact of malignant neoplasms on musculoskeletal system in children (literature review)

Because of the successful implementation of modern treatment technologies at any stage of therapy of children with oncohematological diseases, their overall and disease-free survival has increased significantly. According to recent observations, 80 % of children after the completion of a special ant...

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Main Authors: O. A. Tikhonova, N. Yu. Krutikova, A. F. Karelin, E. V. Zhukovskaya, A. G. Rumyantsev
Format: Article
Language:Russian
Published: ABV-press 2019-01-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/321
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author O. A. Tikhonova
N. Yu. Krutikova
A. F. Karelin
E. V. Zhukovskaya
A. G. Rumyantsev
author_facet O. A. Tikhonova
N. Yu. Krutikova
A. F. Karelin
E. V. Zhukovskaya
A. G. Rumyantsev
author_sort O. A. Tikhonova
collection DOAJ
description Because of the successful implementation of modern treatment technologies at any stage of therapy of children with oncohematological diseases, their overall and disease-free survival has increased significantly. According to recent observations, 80 % of children after the completion of a special antitumor treatment continue to have changes of different organs. Almost all patients are at risk for late complications from the musculoskeletal system but little attention is paid to this issue. Evaluation of long-term complications from the musculoskeletal system and mineral metabolism in patients, development of their complex rehabilitation and prevention is an actual problem of pediatric oncology and hematology. This review summarizes data on long-term complications from the musculoskeletal system after special therapy. The necessity of diagnostics approaches harmonization and correction of not only the most common complications, but also little studied conditions, such as reduction of bone mineralization, is shown. It is noted that multidisciplinary rehabilitation treatment of children in remission can not only correct the consequences of the underlying disease, concomitant pathology and the consequences of special therapy but also reduce the disability of children.
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institution Kabale University
issn 1818-8346
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publishDate 2019-01-01
publisher ABV-press
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series Онкогематология
spelling doaj-art-4da2a74dc48c4000864f41bb4656a92a2025-08-20T03:35:33ZrusABV-pressОнкогематология1818-83462413-40232019-01-01134606610.17650/1818-8346-2019-13-4-60-66293Impact of malignant neoplasms on musculoskeletal system in children (literature review)O. A. Tikhonova0N. Yu. Krutikova1A. F. Karelin2E. V. Zhukovskaya3A. G. Rumyantsev4Smolensk State Medical UniversitySmolensk State Medical UniversityDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and ImmunologyDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and ImmunologyDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and ImmunologyBecause of the successful implementation of modern treatment technologies at any stage of therapy of children with oncohematological diseases, their overall and disease-free survival has increased significantly. According to recent observations, 80 % of children after the completion of a special antitumor treatment continue to have changes of different organs. Almost all patients are at risk for late complications from the musculoskeletal system but little attention is paid to this issue. Evaluation of long-term complications from the musculoskeletal system and mineral metabolism in patients, development of their complex rehabilitation and prevention is an actual problem of pediatric oncology and hematology. This review summarizes data on long-term complications from the musculoskeletal system after special therapy. The necessity of diagnostics approaches harmonization and correction of not only the most common complications, but also little studied conditions, such as reduction of bone mineralization, is shown. It is noted that multidisciplinary rehabilitation treatment of children in remission can not only correct the consequences of the underlying disease, concomitant pathology and the consequences of special therapy but also reduce the disability of children.https://oncohematology.abvpress.ru/ongm/article/view/321disease-free survivalchildneoplasmmineral exchangemusculoskeletal system
spellingShingle O. A. Tikhonova
N. Yu. Krutikova
A. F. Karelin
E. V. Zhukovskaya
A. G. Rumyantsev
Impact of malignant neoplasms on musculoskeletal system in children (literature review)
Онкогематология
disease-free survival
child
neoplasm
mineral exchange
musculoskeletal system
title Impact of malignant neoplasms on musculoskeletal system in children (literature review)
title_full Impact of malignant neoplasms on musculoskeletal system in children (literature review)
title_fullStr Impact of malignant neoplasms on musculoskeletal system in children (literature review)
title_full_unstemmed Impact of malignant neoplasms on musculoskeletal system in children (literature review)
title_short Impact of malignant neoplasms on musculoskeletal system in children (literature review)
title_sort impact of malignant neoplasms on musculoskeletal system in children literature review
topic disease-free survival
child
neoplasm
mineral exchange
musculoskeletal system
url https://oncohematology.abvpress.ru/ongm/article/view/321
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AT nyukrutikova impactofmalignantneoplasmsonmusculoskeletalsysteminchildrenliteraturereview
AT afkarelin impactofmalignantneoplasmsonmusculoskeletalsysteminchildrenliteraturereview
AT evzhukovskaya impactofmalignantneoplasmsonmusculoskeletalsysteminchildrenliteraturereview
AT agrumyantsev impactofmalignantneoplasmsonmusculoskeletalsysteminchildrenliteraturereview