In silico design and in vitro validation of a multi-epitope peptide vaccine targeting triple-negative breast cancer

Aims and objectivesThis study aimed to identify immunodominant epitopes from a panel of triple-negative breast cancer (TNBC)-associated proteins—MZF-1, Mucin-1, SOX-9, Keratin 5, Keratin 14, Twist1, and Progranulin (GP88)—to design multi-epitope peptide vaccines capable of eliciting robust anti-tumo...

Full description

Saved in:
Bibliographic Details
Main Authors: Pengjun Zhou, Xing Shi, Jinquan Xia, Hong Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1611991/full
Tags: Add Tag
No Tags, Be the first to tag this record!