Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson’s disease in rats

Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson’s disease in rats

Abstract Background Parkinson’s disease (PD) is a multifactorial disease that involves genetic and environmental factors, which play an essential role in the pathogenesis of PD. Mesenchymal stem cells release a set of bioactive molecules called “secretome” that regulates intercellular communication...

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Bibliographic Details
Main Authors: Mahesh Ramalingam, Sujeong Jang, Jinsu Hwang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
Alpha-synuclein
Autophagy
Exosomes
Neuronal markers
Protein kinases
Online Access:https://doi.org/10.1186/s13287-025-04306-5
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