Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa

Abstract The pathogen Pseudomonas aeruginosa enhances its virulence and antibiotic resistance upon formation of durable biofilms. The exopolysaccharides Pel, Psl and alginate essentially contribute to the biofilm matrix, but their secretion mechanisms are barely understood. Here, we reveal the archi...

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Bibliographic Details
Main Authors: Marius Benedens, Cristian Rosales-Hernandez, Sabine A. P. Straathof, Jennifer Loschwitz, Otto Berninghausen, Giovanni Maglia, Roland Beckmann, Alexej Kedrov
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60605-8
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