HAPIR: a refined Hallmark gene set-based machine learning approach for predicting immunotherapy response in cancer patients

Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, yet the response rate remains limited, with only about 30% of solid tumor patients benefiting. Identifying reliable biomarkers to predict ICIs response remains a significant challenge. In this study, we proposed a ref...

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Bibliographic Details
Main Authors: Mengqin Yuan, Haizhou Liu, Yu-e Huang, Fei Hou, Lihong Wang, Quan Wang, Wei Jiang
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00992-9
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