HAPIR: a refined Hallmark gene set-based machine learning approach for predicting immunotherapy response in cancer patients
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, yet the response rate remains limited, with only about 30% of solid tumor patients benefiting. Identifying reliable biomarkers to predict ICIs response remains a significant challenge. In this study, we proposed a ref...
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| Main Authors: | Mengqin Yuan, Haizhou Liu, Yu-e Huang, Fei Hou, Lihong Wang, Quan Wang, Wei Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-00992-9 |
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