SYNTHESIS OF 1,2,4-TRIAZINO [3,4-C] [I ,2,4] BENZOTRIAZINE, A NOVEL HETEROCYCLIC SYSTEM
3-Mercapto-1,2,4 benzotriazine (1) was methylated by methyl iodide in the presence of base to afford 1,2-dihydro-3-methyhercapto-1, 2,4 benzotriazine (2). The latter was reacted with hydrazine hydrate to give the corresponding 3-hydrazine derivative (3). Compound (3) on condensation with phenacyl br...
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| Format: | Article |
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| Language: | English |
| Published: |
University of Tehran
1997-12-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
| Online Access: | https://jsciences.ut.ac.ir/article_31277_bcdaca4911a22c0b00f6b3f3ab360f56.pdf |
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| Summary: | 3-Mercapto-1,2,4 benzotriazine (1) was methylated by methyl iodide in the
presence of base to afford 1,2-dihydro-3-methyhercapto-1, 2,4 benzotriazine (2).
The latter was reacted with hydrazine hydrate to give the corresponding 3-hydrazine
derivative (3). Compound (3) on condensation with phenacyl bromide gave 3-
phenacyl hydrazino l,2,4-benzotriazine (4). PPA cyclization of the ketone (4)
yielded lH, 2H, 10H-4-phenyl-triazino [3,4-c]- 1,2,4-benzotriazine (5). Triazino
benzotriazine (5) is a novel heterocyclic system and is reported for the first time. |
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| ISSN: | 1016-1104 2345-6914 |