Different populations of mouse egg cortical vesicles are responsible for post-fertilization zinc sparks and proteolysis of the zona pellucida
Summary: Fertilization of mouse eggs by sperm triggers exocytosis of cortical granules, releasing zinc sparks as well as ovastacin that cleaves ZP2 in the zona pellucida. The mechanism by which zinc accumulates in cortical granules prior to fertilization has yet to be determined. We microinjected cR...
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| Main Authors: | Omar José, Boris Baibakov, Jurrien Dean |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225008673 |
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