A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?

Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggestin...

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Main Authors: Theofano Orfanelli, Chi-Son Kim, Sally F. Vitez, James Van Gurp, Neeti Misra
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2016/6810368
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author Theofano Orfanelli
Chi-Son Kim
Sally F. Vitez
James Van Gurp
Neeti Misra
author_facet Theofano Orfanelli
Chi-Son Kim
Sally F. Vitez
James Van Gurp
Neeti Misra
author_sort Theofano Orfanelli
collection DOAJ
description Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a growing mass on the right labium majus at 20 weeks’ gestation. The patient also developed a smaller mass on the left labium majus at 37 weeks’ gestation. The patient underwent a primary cesarean section with resection of the right labial mass, with a final diagnosis of aggressive angiomyxoma. The lesion on her left labium majus resolved spontaneously postpartum. This case report supports a hormonal involvement in this tumor.
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spelling doaj-art-4d886916eba64ed9b5384bd6fbc768112025-08-20T03:36:22ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922016-01-01201610.1155/2016/68103686810368A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?Theofano Orfanelli0Chi-Son Kim1Sally F. Vitez2James Van Gurp3Neeti Misra4Department of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901, USADepartment of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901, USADepartment of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901, USADepartment of Pathology, Rutgers-Robert Wood Johnson Medical School, One Robert Wood Johnson Place, MEB 212, New Brunswick, NJ 08903, USADepartment of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901, USAAggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a growing mass on the right labium majus at 20 weeks’ gestation. The patient also developed a smaller mass on the left labium majus at 37 weeks’ gestation. The patient underwent a primary cesarean section with resection of the right labial mass, with a final diagnosis of aggressive angiomyxoma. The lesion on her left labium majus resolved spontaneously postpartum. This case report supports a hormonal involvement in this tumor.http://dx.doi.org/10.1155/2016/6810368
spellingShingle Theofano Orfanelli
Chi-Son Kim
Sally F. Vitez
James Van Gurp
Neeti Misra
A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
Case Reports in Obstetrics and Gynecology
title A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
title_full A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
title_fullStr A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
title_full_unstemmed A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
title_short A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?
title_sort case report of aggressive angiomyxoma in pregnancy do hormones play a role
url http://dx.doi.org/10.1155/2016/6810368
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