Meta‐Analysis of Recurrence‐Free Survival or Disease‐Free Survival as a Potential Surrogate Endpoint for Overall Survival in Esophageal Cancer Trials

Meta‐Analysis of Recurrence‐Free Survival or Disease‐Free Survival as a Potential Surrogate Endpoint for Overall Survival in Esophageal Cancer Trials

ABSTRACT Background Cancer trials increasingly use surrogate endpoints, but it is unclear how well recurrence‐free survival (RFS) or disease‐free survival (DFS) specifically predict overall survival (OS) in resectable esophageal cancer (EC). Methods A systematic literature review identified trials w...

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Bibliographic Details
Main Authors: Uchechukwu Love Anyaduba, Oluwatosin Qawiyy Orababa, Zion Faye, Nazia Rashid, Jason Shafrin, Gregory Reardon
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Reports
Subjects:
disease‐free survival
esophageal cancer
esophageal neoplasms
local
neoplasm recurrence
randomized controlled trial
Online Access:https://doi.org/10.1002/cnr2.70195
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https://doi.org/10.1002/cnr2.70195

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