Pan-Genome Identification and Expression Analysis of Lipoxygenase Genes in Cucumber

Lipoxygenase (LOX) is a dioxygenase that contains non-heme iron and plays a crucial role in regulating plant growth and development, signal transduction, and responses to both biotic and abiotic stresses. In this study, we identified 24 <i>CsLOXs</i> from the pan-genome of 12 cucumber (&...

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Bibliographic Details
Main Authors: Haiyu Xu, Kun Liu, Lili Zhao, Chunhua Chen, Lina Wang, Zhonghai Ren
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Agriculture
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Online Access:https://www.mdpi.com/2077-0472/15/3/245
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Summary:Lipoxygenase (LOX) is a dioxygenase that contains non-heme iron and plays a crucial role in regulating plant growth and development, signal transduction, and responses to both biotic and abiotic stresses. In this study, we identified 24 <i>CsLOXs</i> from the pan-genome of 12 cucumber (<i>Cucumis sativus</i> L.) accessions, with most CsLOX proteins exhibiting amino acid variations. To elucidate their functions, we examined the phylogenetic relationships, gene structures, conserved domains, promoter cis-elements, and collinearity of the 24 <i>CsLOXs</i> from the newly updated genome version 4.0 of ‘Chinese Long 9930’. The results indicated that <i>CsLOXs</i> can be categorized into three subfamilies: 9-LOX, Type I 13-LOX, and Type II 13-LOX. Additionally, promoter analysis revealed that the promoters of <i>CsLOXs</i> contain various cis-elements related to stress and hormone responses. The expression of <i>CsLOXs</i> demonstrated tissue specificity, with each <i>CsLOX</i> expressed in at least one tissue, and six <i>CsLOXs</i> expressed across all tissues. Furthermore, in the transcriptome data of cucumber responses to heat, cold, powdery mildew (PM), downy mildew (DM), and gray mold (GM) stresses, eight, four, eight, eight, and four <i>CsLOXs</i> exhibited differential expression, respectively. Notably, <i>CsLOX22</i> responded to heat, cold, DM, and GM stresses. Our results provided a reference for further exploring the functions of <i>CsLOXs</i> in cucumber.
ISSN:2077-0472