Pentagalloyl Glucose from <i>Bouea macrophylla</i> Suppresses the Epithelial–Mesenchymal Transition and Synergizes the Doxorubicin-Induced Anticancer and Anti-Migration Effects in Triple-Negative Breast Cancer

Pentagalloyl Glucose from <i>Bouea macrophylla</i> Suppresses the Epithelial–Mesenchymal Transition and Synergizes the Doxorubicin-Induced Anticancer and Anti-Migration Effects in Triple-Negative Breast Cancer

<b>Background:</b> Triple-negative breast cancer (TNBC) represents an aggressive form of breast cancer with few available therapeutic options. Chemotherapy, particularly with drugs like doxorubicin (DOX), remains the cornerstone of treatment for this challenging subtype. However, the cli...

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Bibliographic Details
Main Authors: Jiraporn Kantapan, Phattarawadee Innuan, Sarawut Kongkarnka, Padchanee Sangthong, Nathupakorn Dechsupa
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
pentagalloyl glucose (PGG)
triple-negative breast cancer (TNBC)
epithelial–mesenchymal transition (EMT)
doxorubicin
synergistic
Online Access:https://www.mdpi.com/1424-8247/17/12/1729
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