Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

Tissue Transglutaminase-Regulated Transformed Growth Factor-β1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

Transforming growth factor (TGF-β1) is among the strongest factors of liver fibrogenesis, but its association with Schistosoma-caused liver fibrosis is controversial. Tissue transglutaminase (tTG) is the principal enzyme controlling TGF-β1 maturation and contributes to Sj-infected liver fibrosis. He...

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Bibliographic Details
Main Authors:	Juanjuan Tang, Xunmin Zhu, Jingjing Zhao, Mingchiu Fung, Yinyan Li, Zhiyan Gao, Suikai Yan, Xiaomin Li, Xiaofang Ji, Fang Su, Zi Li
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2015/659378
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