Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures

ABSTRACT. Epilepsy with myoclonic–atonic seizures (EMAS), or Doose syndrome, is characterized by the presence of atonic–myoclonic seizures that begin in childhood between 7 months and 6 years of age, which may present with cognitive and behavioral changes. Objective: The aim of this present study w...

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Main Authors: Ericka Olívia Rodrigues Samoiloff, Denise Harumi Nakanishi, Eliane Correa Miotto
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento 2025-07-01
Series:Dementia & Neuropsychologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642025000100415&lng=en&tlng=en
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author Ericka Olívia Rodrigues Samoiloff
Denise Harumi Nakanishi
Eliane Correa Miotto
author_facet Ericka Olívia Rodrigues Samoiloff
Denise Harumi Nakanishi
Eliane Correa Miotto
author_sort Ericka Olívia Rodrigues Samoiloff
collection DOAJ
description ABSTRACT. Epilepsy with myoclonic–atonic seizures (EMAS), or Doose syndrome, is characterized by the presence of atonic–myoclonic seizures that begin in childhood between 7 months and 6 years of age, which may present with cognitive and behavioral changes. Objective: The aim of this present study was to evaluate adaptive behavior, performance on intelligence and neuropsychological tests, and verify the association of autism spectrum disorder and attention deficit hyperactivity disorder in patients diagnosed with EMAS compared with a control group of healthy children. Methods: We included nine patients with EMAS and nine healthy controls, assessed by scales of adaptive behavior development, autism spectrum disorder, attention deficit and hyperactivity, and intelligence and neuropsychological tests. Results: The results revealed that in the intelligence and neuropsychological tests, there was a significant difference between the groups (p>0.05), with worse performance for the EMAS group. In the latter group, eight patients showed some symptoms of attention deficit hyperactivity disorder and none showed symptoms of autism spectrum disorder or changes in adaptive behavior. Conclusion: These findings show the relevance of investigating cognitive and behavioral profiles in this population in order to address specific impairments in their everyday life activities.
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series Dementia & Neuropsychologia
spelling doaj-art-4d6840a3cfdd4fcb90addac97c1c35642025-08-20T03:25:19ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642025-07-011910.1590/1980-5764-dn-2024-0249Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizuresEricka Olívia Rodrigues Samoiloffhttps://orcid.org/0009-0005-4488-8712Denise Harumi Nakanishihttps://orcid.org/0000-0001-5934-8675Eliane Correa Miottohttps://orcid.org/0000-0003-2711-1627ABSTRACT. Epilepsy with myoclonic–atonic seizures (EMAS), or Doose syndrome, is characterized by the presence of atonic–myoclonic seizures that begin in childhood between 7 months and 6 years of age, which may present with cognitive and behavioral changes. Objective: The aim of this present study was to evaluate adaptive behavior, performance on intelligence and neuropsychological tests, and verify the association of autism spectrum disorder and attention deficit hyperactivity disorder in patients diagnosed with EMAS compared with a control group of healthy children. Methods: We included nine patients with EMAS and nine healthy controls, assessed by scales of adaptive behavior development, autism spectrum disorder, attention deficit and hyperactivity, and intelligence and neuropsychological tests. Results: The results revealed that in the intelligence and neuropsychological tests, there was a significant difference between the groups (p>0.05), with worse performance for the EMAS group. In the latter group, eight patients showed some symptoms of attention deficit hyperactivity disorder and none showed symptoms of autism spectrum disorder or changes in adaptive behavior. Conclusion: These findings show the relevance of investigating cognitive and behavioral profiles in this population in order to address specific impairments in their everyday life activities.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642025000100415&lng=en&tlng=enEpilepsies, MyoclonicAttention Deficit Disorder with HyperactivityAutistic DisorderNeuropsychological Tests
spellingShingle Ericka Olívia Rodrigues Samoiloff
Denise Harumi Nakanishi
Eliane Correa Miotto
Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
Dementia & Neuropsychologia
Epilepsies, Myoclonic
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Neuropsychological Tests
title Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
title_full Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
title_fullStr Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
title_full_unstemmed Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
title_short Cognitive and behavioral performance in children with epilepsy with myoclonic–atonic seizures
title_sort cognitive and behavioral performance in children with epilepsy with myoclonic atonic seizures
topic Epilepsies, Myoclonic
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Neuropsychological Tests
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642025000100415&lng=en&tlng=en
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AT deniseharuminakanishi cognitiveandbehavioralperformanceinchildrenwithepilepsywithmyoclonicatonicseizures
AT elianecorreamiotto cognitiveandbehavioralperformanceinchildrenwithepilepsywithmyoclonicatonicseizures